Cellular functions and molecular mechanisms of the ESCRT membrane-scission machinery
L Christ, C Raiborg, EM Wenzel, C Campsteijn… - Trends in biochemical …, 2017 - cell.com
The endosomal sorting complex required for transport (ESCRT) machinery is an assembly of
protein subcomplexes (ESCRT I-III) that cooperate with the ATPase VPS4 to mediate …
protein subcomplexes (ESCRT I-III) that cooperate with the ATPase VPS4 to mediate …
ESCRT and membrane protein ubiquitination
SM Migliano, D Teis - Endocytosis and Signaling, 2018 - Springer
The ubiquitin-dependent degradation of membrane proteins via the multivesicular body
(MVB) pathway requires the Endosomal Sorting Complexes Required for Transport …
(MVB) pathway requires the Endosomal Sorting Complexes Required for Transport …
PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target
S Singh, NY Yeat, YT Wang, SY Lin, IY Kuo… - Cell Death & …, 2023 - nature.com
Aberrant overexpression or activation of EGFR drives the development of non-small cell
lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by …
lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by …
ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis
S Tang, NJ Buchkovich, WM Henne, S Banjade, YJ Kim… - Elife, 2016 - elifesciences.org
The endosomal sorting complexes required for transport (ESCRT) pathway facilitates
multiple fundamental membrane remodeling events. Previously, we determined X-ray crystal …
multiple fundamental membrane remodeling events. Previously, we determined X-ray crystal …
Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX
T Shirasaki, H Feng, HME Duyvesteyn… - PLoS …, 2022 - journals.plos.org
Although picornaviruses are conventionally considered 'nonenveloped', members of
multiple picornaviral genera are released nonlytically from infected cells in extracellular …
multiple picornaviral genera are released nonlytically from infected cells in extracellular …
Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis
Endosomal sorting complexes required for transport (ESCRT-0,-I,-II,-III) execute cargo
sorting and intralumenal vesicle (ILV) formation during conversion of endosomes to …
sorting and intralumenal vesicle (ILV) formation during conversion of endosomes to …
When membranes need an ESCRT: endosomal sorting and membrane remodelling in health and disease
V Alfred, T Vaccari - Swiss Medical Weekly, 2016 - air.unimi.it
Originally discovered as regulators of cargo sorting during endosomal trafficking, ESCRT
(endosomal sorting complexes required for transport) proteins are emerging as flexible …
(endosomal sorting complexes required for transport) proteins are emerging as flexible …
Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase
N Pashkova, L Yu, NJ Schnicker… - Molecular biology of …, 2021 - Am Soc Cell Biol
The family of Bro1 proteins coordinates the activity of the Endosomal Sorting Complexes
Required for Transport (ESCRTs) to mediate a number of membrane remodeling events …
Required for Transport (ESCRTs) to mediate a number of membrane remodeling events …
Seeking closure: how do herpesviruses recruit the cellular ESCRT apparatus?
J Barnes, DW Wilson - Journal of virology, 2019 - Am Soc Microbiol
The Herpesviridae are structurally complex DNA viruses whose capsids undergo primary
envelopment at the inner nuclear membrane and secondary envelopment at organelles in …
envelopment at the inner nuclear membrane and secondary envelopment at organelles in …
Structural basis for selective interaction between the ESCRT regulator HD-PTP and UBAP1
D Gahloth, C Levy, G Heaven, F Stefani, L Wunderley… - Structure, 2016 - cell.com
Endosomal sorting complexes required for transport (ESCRTs) are essential for ubiquitin-
dependent degradation of mitogenic receptors, a process often compromised in cancer …
dependent degradation of mitogenic receptors, a process often compromised in cancer …