Resident tissue macrophages (RTMs) encompass a highly diverse set of cells abundantly
present in every tissue and organ. RTMs are recognized as central players in innate immune …

Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

Most organs have tissue-resident immune cells. Human organoids lack these immune cells,
which limits their utility in modeling many normal and disease processes. Here, we describe …

Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt
to diverse tissue microenvironments and perform various functions. Traditionally categorized …

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common life‐
threatening syndrome with no effective pharmacotherapy. Sepsis‐related ARDS is the main …

Lung cancer is one of the most common cancers worldwide and a leading cause of cancer-
related deaths. Macrophages play a key role in the immune response and the tumour …

Tumor-associated macrophages are transcriptionally heterogeneous, but the spatial
distribution and cell interactions that shape macrophage tissue roles remain poorly …

Fructose is associated with colorectal cancer tumorigenesis and metastasis through
ketohexokinase-mediated metabolism in the colorectal epithelium, yet its role in the tumor …

Mononuclear phagocytes (MP), ie, monocytes, macrophages, and dendritic cells (DCs), are
essential for immune homeostasis via their capacities to clear pathogens, pathogen …

Single-cell approaches have shone a spotlight on discrete context-specific tissue
macrophage states, deconstructed to their most minute details. Machine-learning (ML) …