Manganese‐enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations

AC Silva, JH Lee, I Aoki… - NMR in Biomedicine: An …, 2004 - Wiley Online Library
Manganese‐enhanced MRI (MEMRI) is being increasingly used for MRI in animals due to
the unique T1 contrast that is sensitive to a number of biological processes. Three specific …

Cellular MR imaging

M Modo, M Hoehn, JWM Bulte - Molecular imaging, 2005 - journals.sagepub.com
Cellular MR imaging is a young field that aims to visualize targeted cells in living organisms.
In order to provide a different signal intensity of the targeted cell, they are either labeled with …

Springer Series in Statistics

P Bickel, P Diggle, S Fienberg, U Gather - 2005 - Springer
Hidden Markov models—most often abbreviated to the acronym “HMMs”—are one of the
most successful statistical modelling ideas that have came up in the last forty years: the use …

Physical principles for scalable neural recording

AH Marblestone, BM Zamft, YG Maguire… - Frontiers in …, 2013 - frontiersin.org
Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond
resolution is a challenge beyond the limits of existing techniques in neuroscience. Entirely …

In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI

I Aoki, YJL Wu, AC Silva, RM Lynch, AP Koretsky - Neuroimage, 2004 - Elsevier
Visualizing brain anatomy in vivo could provide insight into normal and pathophysiology.
Here it is demonstrated that neuroarchitecture can be detected in the rodent brain using MRI …

Manganese-enhanced MRI: an exceptional tool in translational neuroimaging

AC Silva, NA Bock - Schizophrenia bulletin, 2008 - academic.oup.com
The metal manganese is a potent magnetic resonance imaging (MRI) contrast agent that is
essential in cell biology. Manganese-enhanced magnetic resonance imaging (MEMRI) is …

Manganese‐enhanced magnetic resonance imaging of mouse brain after systemic administration of MnCl2: Dose‐dependent and temporal evolution of T1 contrast

JH Lee, AC Silva, H Merkle… - Magnetic Resonance in …, 2005 - Wiley Online Library
Manganese is a useful contrast agent for MRI of animals. Previously, it has been shown that
systemic doses of MnCl2 provide unique contrast in the rodent brain, enabling visualization …

Manganese-enhanced magnetic resonance imaging (MEMRI)

CA Massaad, RG Pautler - Magnetic Resonance Neuroimaging: Methods …, 2011 - Springer
The use of manganese ions (Mn 2+) as an MRI contrast agent was introduced over 20 years
ago in studies of Mn 2+ toxicity in anesthetized rats (1). Manganese-enhanced MRI (MEMRI) …

Water diffusion in brain cortex closely tracks underlying neuronal activity

T Tsurugizawa, L Ciobanu… - Proceedings of the …, 2013 - National Acad Sciences
Neuronal activity results in a local increase in blood flow. This concept serves as the basis
for functional MRI. Still, this approach remains indirect and may fail in situations interfering …

Mapping the connectome: multi-level analysis of brain connectivity

TB Leergaard, CC Hilgetag, O Sporns - Frontiers in neuroinformatics, 2012 - frontiersin.org
Figure 1| From multi-modal connectivity data to integrated connectomes. Image panels
illustrating recent progress, selected and modified from contributions to the Research Topic …