pH-Sensitive nanogels for drug delivery in cancer therapy

Z Li, J Huang, J Wu - Biomaterials Science, 2021 - pubs.rsc.org
As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …

Targeting multiple signaling pathways in cancer: The rutin therapeutic approach

Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

Nanogels as target drug delivery systems in cancer therapy: A review of the last decade

AA Attama, PO Nnamani, OB Onokala… - Frontiers in …, 2022 - frontiersin.org
Cancer is an important cause of morbidity and mortality worldwide, irrespective of the level
of human development. Globally, it was estimated that there were 19.3 million new cases of …

Polyacrylic acid-based drug delivery systems: A comprehensive review on the state-of-art

G Dalei, S Das - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Polyacrylic acid (PAA)-based drug carrier systems have garnered much significance
towards the delivery of various therapeutic agents via different administration routes for the …

Quercetin-and rutin-based nano-formulations for cancer treatment: A systematic review of improved efficacy and molecular mechanisms

M Ghanbari-Movahed, A Mondal, MH Farzaei… - Phytomedicine, 2022 - Elsevier
Background Natural products, with incredible chemical diversity, have been widely studied
for their antitumor potential. Quercetin (QU) and quercetin glycoside (rutin), both …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Recent developments and applications of smart nanoparticles in biomedicine

S Campora, G Ghersi - Nanotechnology Reviews, 2022 - degruyter.com
Over the last decades, nanotechnology applied in medicine (nanomedicine) has sparked
great interest from the scientific community, thanks to the possibility to engineer …

Recent developments in chitosan based microgels and their hybrids

A Ahmad, A Hassan, PG Roy, S Zhou, A Irfan… - International Journal of …, 2024 - Elsevier
Chitosan based microgels have gained great attention because of their chemical stability,
biocompatibility, easy functionalization and potential uses in numerous fields. Production …

A review on rutin-loaded nanocarriers: Fundamentals, bioavailability, application in functional foods, and challenges

A Rashidinejad, C Dima, AC Karaca… - European Polymer Journal, 2024 - Elsevier
Rutin, a hydrophobic flavonoid found in various fruits and vegetables, has potential health
benefits. However, its therapeutic use is limited due to poor bioavailability and stability …

Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update

BNHM Neerooa, LT Ooi, K Shameli, NA Dahlan… - Gels, 2021 - mdpi.com
With cancer remaining as one of the main causes of deaths worldwide, many studies are
undergoing the effort to look for a novel and potent anticancer drug. Nanoparticles (NPs) are …