Making sense out of spinal cord somatosensory development

HC Lai, RP Seal, JE Johnson - Development, 2016 - journals.biologists.com
The spinal cord integrates and relays somatosensory input, leading to complex motor
responses. Research over the past couple of decades has identified transcription factor …

Vertebrate sensory ganglia: common and divergent features of the transcriptional programs generating their functional specialization

S Vermeiren, EJ Bellefroid, S Desiderio - Frontiers in Cell and …, 2020 - frontiersin.org
Sensory fibers of the peripheral nervous system carry sensation from specific sense
structures or use different tissues and organs as receptive fields, and convey this information …

A lamprey neural cell type atlas illuminates the origins of the vertebrate brain

F Lamanna, F Hervas-Sotomayor, AP Oel… - Nature Ecology & …, 2023 - nature.com
The vertebrate brain emerged more than~ 500 million years ago in common evolutionary
ancestors. To systematically trace its cellular and molecular origins, we established a …

The multifaceted roles of PRDM16: adipose biology and beyond

J Chi, P Cohen - Trends in Endocrinology & Metabolism, 2016 - cell.com
The PRDM [PRDI-BFI (positive regulatory domain I-binding factor 1) and RIZ1
(retinoblastoma protein-interacting zinc finger gene 1) homologous domain containing] …

A single cell transcriptome atlas of the developing zebrafish hindbrain

M Tambalo, R Mitter, DG Wilkinson - Development, 2020 - journals.biologists.com
Segmentation of the vertebrate hindbrain leads to the formation of rhombomeres, each with
a distinct anteroposterior identity. Specialised boundary cells form at segment borders that …

Prdm12 directs nociceptive sensory neuron development by regulating the expression of the NGF receptor TrkA

S Desiderio, S Vermeiren, C Van Campenhout… - Cell reports, 2019 - cell.com
In humans, many cases of congenital insensitivity to pain (CIP) are caused by mutations of
components of the NGF/TrkA signaling pathway, which is required for survival and …

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates

JL Plouhinec, S Medina-Ruiz, C Borday, E Bernard… - PLoS …, 2017 - journals.plos.org
During vertebrate neurulation, the embryonic ectoderm is patterned into lineage progenitors
for neural plate, neural crest, placodes and epidermis. Here, we use Xenopus laevis …

The duality of PRDM proteins: epigenetic and structural perspectives

F Di Tullio, M Schwarz, H Zorgati, S Mzoughi… - The FEBS …, 2022 - Wiley Online Library
PRDF1 and RIZ1 homology domain containing (PRDMs) are a subfamily of Krüppel‐like
zinc finger proteins controlling key processes in metazoan development and in cancer …

PRDM12 is required for initiation of the nociceptive neuron lineage during neurogenesis

L Bartesaghi, Y Wang, P Fontanet, S Wanderoy… - Cell reports, 2019 - cell.com
The sensation of pain is essential for the preservation of the functional integrity of the body.
However, the key molecular regulators necessary for the initiation of the development of …

PRDM12 in health and diseases

M Rienzo, E Di Zazzo, A Casamassimi… - International Journal of …, 2021 - mdpi.com
PRDM12 is a member of the PRDI-BF1 (positive regulatory domain I-binding factor 1)
homologous domain (PRDM)-containing protein family, a subfamily of Kruppel-like zinc …