Exploring the efficacy of natural products in alleviating Alzheimer's disease
Alzheimer's disease (hereafter AD) is a progressive neurodegenerative disorder that affects
the central nervous system. There are multiple factors that cause AD, viz., accumulation of …
the central nervous system. There are multiple factors that cause AD, viz., accumulation of …
My what big eyes you have: How the Drosophila retina grows
JP Kumar - Developmental neurobiology, 2011 - Wiley Online Library
The compound eye of the fruit fly, Drosophila melanogaster, has for decades been used
extensively to study a number of critical developmental processes including tissue …
extensively to study a number of critical developmental processes including tissue …
N-Acetyltransferase 9 ameliorates Aβ42-mediated neurodegeneration in the Drosophila eye
P Deshpande, AV Chimata, E Snider, A Singh… - Cell Death & …, 2023 - nature.com
Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, manifests as
accumulation of amyloid-beta-42 (Aβ42) plaques and intracellular accumulation of …
accumulation of amyloid-beta-42 (Aβ42) plaques and intracellular accumulation of …
[HTML][HTML] Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo
Abstract Amyotrophic Lateral Sclerosis (ALS), a late-onset neurodegenerative disorder
characterized by the loss of motor neurons in the central nervous system, has no known cure …
characterized by the loss of motor neurons in the central nervous system, has no known cure …
Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer's Disease
Background The progressive neurodegenerative disorder Alzheimer's disease (AD)
manifests as loss of cognitive functions, and finally leads to death of the affected individual …
manifests as loss of cognitive functions, and finally leads to death of the affected individual …
Hippo signaling: bridging the gap between cancer and neurodegenerative disorders
N Gogia, AV Chimata, P Deshpande… - Neural Regeneration …, 2021 - journals.lww.com
During development, regulation of organ size requires a balance between cell proliferation,
growth and cell death. Dysregulation of these fundamental processes can cause a variety of …
growth and cell death. Dysregulation of these fundamental processes can cause a variety of …
miR-277 targets the proapoptotic gene-hid to ameliorate Aβ42-mediated neurodegeneration in Alzheimer's model
P Deshpande, CY Chen, AV Chimata, JC Li… - Cell Death & …, 2024 - nature.com
Abstract Alzheimer's disease (AD), an age-related progressive neurodegenerative disorder,
exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the …
exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the …
Lobe and Serrate are required for cell survival during early eye development in Drosophila
A Singh, X Shi, KW Choi - 2006 - journals.biologists.com
Organogenesis involves an initial surge of cell proliferation, leading to differentiation. This is
followed by cell death in order to remove extra cells. During early development, there is little …
followed by cell death in order to remove extra cells. During early development, there is little …
A glimpse into dorso‐ventral patterning of the Drosophila eye
During organogenesis in all multi‐cellular organisms, axial patterning is required to
transform a single layer organ primordium into a three‐dimensional organ. The Drosophila …
transform a single layer organ primordium into a three‐dimensional organ. The Drosophila …
Unraveling Alzheimer's Disease Using Drosophila
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder that predominantly
affects people aged over 65 years. AD is marked by cognitive deficits and memory problems …
affects people aged over 65 years. AD is marked by cognitive deficits and memory problems …