Accelerated evolution and functional divergence of the dim light visual pigment accompanies cichlid colonization of Central America
Cichlids encompass one of the most diverse groups of fishes in South and Central America,
and show extensive variation in life history, morphology, and colouration. While studies of …
and show extensive variation in life history, morphology, and colouration. While studies of …
[HTML][HTML] Puerarin protects against iron overload-induced retinal injury through regulation of iron-handling proteins
Q Song, Y Zhao, Q Li, X Han, J Duan - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Excess iron content can build up in the retina and lead to iron-mediated retinal injury. An
important isoflavone C-glucoside, puerarin, has been reported to be involved in retinal …
important isoflavone C-glucoside, puerarin, has been reported to be involved in retinal …
Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision
GM Castiglione, BSW Chang - Elife, 2018 - elifesciences.org
Trade-offs between protein stability and activity can restrict access to evolutionary
trajectories, but widespread epistasis may facilitate indirect routes to adaptation. This may …
trajectories, but widespread epistasis may facilitate indirect routes to adaptation. This may …
Astragaloside IV protects against retinal iron overload toxicity through iron regulation and the inhibition of MAPKs and NF-κB activation
Q Song, Y Zhao, Y Yang, X Han, J Duan - Toxicology and Applied …, 2021 - Elsevier
Iron overload toxicity has been implicated in retinal pigment epithelial cell injury in age-
related macular degeneration. This study investigates the effects of astragaloside IV (AS-IV) …
related macular degeneration. This study investigates the effects of astragaloside IV (AS-IV) …
An experimental comparison of human and bovine rhodopsin provides insight into the molecular basis of retinal disease
Rhodopsin is the visual pigment that mediates dim‐light vision in vertebrates and is a model
system for the study of retinal disease. The majority of rhodopsin experiments are performed …
system for the study of retinal disease. The majority of rhodopsin experiments are performed …
To see or not to see: Molecular evolution of the rhodopsin visual pigment in neotropical electric fishes
A Van Nynatten, FH Janzen… - … of the Royal …, 2019 - royalsocietypublishing.org
Functional variation in rhodopsin, the dim-light-specialized visual pigment, frequently occurs
in species inhabiting light-limited environments. Variation in visual function can arise …
in species inhabiting light-limited environments. Variation in visual function can arise …
To see or not to see
A Van Nynatten, FH Janzen, K Brochu… - Proceedings: Biological …, 2019 - JSTOR
Functional variation in rhodopsin, the dim-light-specialized visual pigment, frequently occurs
in species inhabiting light-limited environments. Variation in visual function can arise …
in species inhabiting light-limited environments. Variation in visual function can arise …