The role of CBL family ubiquitin ligases in cancer progression and therapeutic strategies
J Ren, L Lv, X Tao, X Zhai, X Chen, H Yu… - Frontiers in …, 2024 - frontiersin.org
The CBL (Casitas B-lineage lymphoma) family, as a class of ubiquitin ligases, can regulate
signal transduction and activate receptor tyrosine kinases through various tyrosine kinase …
signal transduction and activate receptor tyrosine kinases through various tyrosine kinase …
AI‐guided histopathology predicts brain metastasis in lung cancer patients
Brain metastases can occur in nearly half of patients with early and locally advanced (stage I–
III) non‐small cell lung cancer (NSCLC). There are no reliable histopathologic or molecular …
III) non‐small cell lung cancer (NSCLC). There are no reliable histopathologic or molecular …
[HTML][HTML] Values of circulating tumor DNA for non-small cell lung cancer patients receiving neoadjuvant therapy, progress and challenges: a narrative review
S Zhou, C Shen, Y Wang, Z Zhao… - Journal of Thoracic …, 2024 - ncbi.nlm.nih.gov
Methods A search of online databases (PubMed, Embase, Web of Science, Science Direct,
and Cochrane Library) was conducted to evaluate the value of ctDNA in predicting relapse …
and Cochrane Library) was conducted to evaluate the value of ctDNA in predicting relapse …
DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma
S Wei, J Xing, J Chen, L Chen, J Lv, X Chen… - Journal of Experimental …, 2024 - Springer
Background Lung cancer is a malignant tumor with the highest mortality worldwide.
Abnormalities in the ubiquitin proteasome system are considered to be contributed to lung …
Abnormalities in the ubiquitin proteasome system are considered to be contributed to lung …
Association of socioeconomic factors with the receipt of neoadjuvant therapy for patients with non–small cell lung cancer
MM Elbahrawy, MK Kamel… - The Journal of Thoracic …, 2024 - Elsevier
Background Neoadjuvant therapy (NT) will be increasingly used for patients with non–small
cell lung cancer (NSCLC), particularly given the recent approval of neoadjuvant …
cell lung cancer (NSCLC), particularly given the recent approval of neoadjuvant …
Melatonin protects mice from 5-FU hepatotoxicity and improves 5-FU antitumor effects by an apoptotic pathway dependent on cell cycle arrest in A549 human lung …
Objectives This study determined if melatonin (MLT) can be used with 5-fluorouracil (5-FU),
an anticancer drug as adjuvants to reduce A549 lung cancer cell proliferation and sensitise …
an anticancer drug as adjuvants to reduce A549 lung cancer cell proliferation and sensitise …
[HTML][HTML] IGFBP1 promotes the proliferation and migration of lung adenocarcinoma cells through the PPARα pathway
Y Li, X Yang, T Han, J Zhou, Y Liu, J Guo, Z Liu… - Translational …, 2024 - Elsevier
Background The immune status is closely linked to cancer progression, metastasis, and
prognosis. Lipid metabolism, crucial for reshaping immune status, plays a key role in …
prognosis. Lipid metabolism, crucial for reshaping immune status, plays a key role in …
Genome-Wide Methylation Analysis in Two Wild-Type Non-Small Cell Lung Cancer Subgroups with Negative and High PD-L1 Expression
G Hutarew, B Alinger-Scharinger, K Sotlar, TFJ Kraus - Cancers, 2024 - mdpi.com
Simple Summary PD-L1 is a marker that helps determine a tumor's immune status and is
used to select patients for immune therapy. Methylation modifies gene expression by adding …
used to select patients for immune therapy. Methylation modifies gene expression by adding …
[HTML][HTML] Premna puberula root petroleum ether extract inhibits proliferation, migration and invasion, and induces apoptosis through mitochondrial pathway in non …
N Yang, X Jia, Y Yang, J Niu, X Wu, F Ding… - Arabian Journal of …, 2024 - Elsevier
Premna puberula, a medicine food homologous plant, is utilized in the preparation of cold
tofu and as traditional Chinese medicine. This study aimed to identify the chemical …
tofu and as traditional Chinese medicine. This study aimed to identify the chemical …
Integrated analysis of purine metabolism assists in predicting prognosis and treatment decisions for patients with lung adenocarcinoma
T Zhang, R Chen, X Su, M Wang, Q Lu - Heliyon, 2024 - cell.com
The incidence of lung cancer, especially lung adenocarcinoma (LUAD), has recently
increased. Targeted therapy and immunotherapy combined with conventional treatment …
increased. Targeted therapy and immunotherapy combined with conventional treatment …