Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …

Objective The task force of the International Conference of Frailty and Sarcopenia Research
(ICFSR) developed these clinical practice guidelines to overview the current evidence-base …

Background The fraily index is a useful proxy measure of accelerated biological ageing and
in estimating all-cause and cause-specific mortality in older individuals in European and US …

Frailty is a complex age-related clinical condition characterised by a decline in physiological
capacity across several organ systems, with a resultant increased susceptibility to stressors …

Frailty is a common geriatric syndrome and strongly associated with disability, mortality and
hospitalization. Frailty is commonly measured using the frailty index (FI), based on the …

Human gut microbiota is able to influence the host physiology by regulating multiple
processes, including nutrient absorption, inflammation, oxidative stress, immune function …

Frailty, a syndrome characterized by an exaggerated decline in function and reserve of
multiple physiological systems, is common in older patients with heart failure (HF) and is …

Intrinsic capacity, a crucial concept in healthy ageing, is defined by WHO as" the composite
of all the physical and mental capacities that an individual can draw on at any point in time" …

Background A large number of studies have explored the association between frailty and
mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis …