An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering
to replicate the critical physiological environment and functions of the human organs …

Despite the efforts devoted to drug discovery and development, the number of new drug
approvals have been decreasing. Specifically, cardiovascular developments have been …

Epithelial cell function is modulated by mechanical forces imparted by the extracellular
environment. The transmission of forces onto the cytoskeleton by modalities such as …

Microvessels, including arterioles, capillaries, and venules, play an important role in
regulating blood flow, enabling nutrient and waste exchange, and facilitating immune …

Abstract Three‐dimensional (3D) imaging techniques (eg, confocal microscopy) are
commonly used to visualize in vitro models, especially microvasculature on‐a‐chip …

The elastic properties of conductance arteries are one of the most important hemodynamic
functions in the body, and data continue to emerge regarding the importance of their …

The use of microfluidics to make mechanical property measurements is increasingly
common. Fabrication of microfluidic devices has enabled various types of flow control and …

Due to the heterogeneous nature of microvascular structure between organs, it is important
to engineer tailored capillary networks that match their physical properties for biochemical …

Coronavirus disease (COVID-19) causes various vascular and blood-related reactions,
including exacerbated responses. The role of endothelial cells in this acute response is …

Cold‐induced vasoconstriction is a significant contributor that leads to chilblains and
hypothermia in humans. However, current animal models have limitations in replicating cold …