Estrogens mediate profound effects throughout the body and regulate physiological and
pathological processes in both women and men. The low prevalence of many diseases in …

Fibronectin (FN) is a ubiquitous extracellular matrix (ECM) glycoprotein that plays vital roles
during tissue repair. The plasma form of FN circulates in the blood, and upon tissue injury, is …

Estrogens play an important role in the regulation of normal physiology, aging and many
disease states. Although the nuclear estrogen receptors have classically been described to …

Cells of the mammary gland are in intimate contact with other cells and with the extracellular
matrix (ECM), both of which provide not only a biochemical context, but a mechanical …

Using cDNA cloning strategies commonly employed for G protein-coupled receptors
(GPCR), GPCR-30 (GPR30), was isolated from mammalian cells before knowledge of its …

From its origins in how the brain controls the endocrine system via the hypothalamus and
pituitary gland, neuroendocrinology has evolved into a science that now includes hormone …

The G protein-coupled estrogen receptor (GPER) is a seven-transmembrane-domain
receptor that mediates non-genomic estrogen related signaling. After ligand activation …

Aims Fibronectin (FN) has attracted interest in cancer research, owing to its role in tumour
progression. The aims of this study were to investigate the expression and clinical relevance …

GPER possesses structural and functional characteristics shared by members of the G-
protein-coupled receptor (GPCR) superfamily, the largest class of plasma membrane …

Aldosterone is one of the most essential hormones synthesized by the adrenal gland
because it regulates water and electrolyte balance. G protein–coupled estrogen receptor …