Using clear language along with numerous case studies, examples, tables, flow charts, and
schematics Process Scale Bioseparations for the Biopharmaceutical Industry brings together …

Retention of a two small phages (ΦX‐174 and pp7) by direct‐flow small‐virus‐retentive
filters [Viresolve NFP (normal‐flow parvovirus), Virosart CPV (canine parvovirus), Ultipor …

The technique of chromatofocusing was applied to the characterization and purification of
three bacteriophages that are routinely used for testing virus filters: φX174, PR772, and PP7 …

Virus removal using membrane filtration is designed to work by a size exclusion mechanism.
Removal is dictated by the pore size distribution of the membrane and the virus size …

Ensuring the absence of detectable viruses in biopharmaceutical products is imperative from
both a regulatory and patient safety standpoint. Biopharmaceutical viral safety is the result of …

The viral safety of biotechnology products has traditionally been a key concern both of
regulators and industry. 1-6 It has also proven to be a stumbling block for early product …

In the biopharmaceutical industry, column chromatography residuals are routinely assessed
by the direct measurement of mock eluates. In this study, we evaluated virus and other …

After extensive discussion, a largevirus filter test method was drafted. The committee agreed
that the purpose of this method was to provide a common nomenclature system for large …

Separation of viruses and other contaminants from protein therapeutics using anion
exchange membrane adsorbers is a successful new approach to viral clearance; however …

Viruses were so named after the Latin for poison. Among the various descriptives used
tocharacterize viruses,“filterable” was a key attribute. Over the past three decades …