The human stress response has evolved to maintain homeostasis under conditions of real or
perceived stress. This objective is achieved through autoregulatory neural and hormonal …

Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Circadian rhythms play an influential role in nearly all aspects of physiology and behavior in
the vast majority of species on Earth. The biological clockwork that regulates these rhythms …

Sleep–wake cycles are known to be disrupted in people with neurodegenerative disorders.
These findings are now supported by data from animal models for some of these disorders …

Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central
nervous system, ranging from the regulation of gene transcription, cellular signaling …

Circadian rhythms are physiological and behavioural cycles generated by an endogenous
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …

Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

Importance Sleep disturbances are recognized as a common nonmotor complaint in
Parkinson disease but their etiology is poorly understood. Objective To define the sleep and …

This review aims to discuss the evidence supporting the link between chronic stress,
cognitive function and mental health. Over the years, the associations between these …

Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …