Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Background A reported penicillin allergy may compromise receipt of recommended
antibiotic prophylaxis intended to prevent surgical site infections (SSIs). Most patients with a …

Penicillin Allergy Many more patients are labeled as penicillin-allergic than actually are
allergic. The label should be analyzed with skin testing and test exposure. Patients with true …

Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

These guidelines for the treatment of persons who have or are at risk for sexually transmitted
infections (STIs) were updated by CDC after consultation with professionals knowledgeable …

The penicillin allergy label has been consistently linked with deleterious effects that span the
health care spectrum, including suboptimal clinical outcomes, the emergence of bacterial …

Background Having a penicillin allergy label associates with a higher risk for antibiotic
resistance and increased health care use. Objective We sought to assess the accuracy of …

Background Penicillin and other beta-lactam antibiotics are recommended for group B
Streptococcus and cesarean section prophylaxis, but approximately 10% of pregnant …

Drug allergy pathways are standardized approaches for patients reporting prior drug
allergies with the aim of quality improvement and promotion of antibiotic stewardship. At the …