The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …

The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions
of people, most of them neglected populations. The different phases of the disease, the …

Background Despite the adoption of campaigns to interrupt the main vector and to detect
Trypanosoma cruzi in blood banks, millions of people are still chronically infected; however …

Chagas disease is a neglected tropical disease transmitted by the protozoan Trypanosoma
cruzi that lately has been highlighted because several outbreaks attributed to oral …

Nifurtimox is recommended for the treatment of Chagas disease; however, long-term follow-
up data are scarce. This prolonged follow-up phase of the prospective, historically …

There is no consensus on the diagnostic algorithms for many scenarios of Trypanosoma
cruzi infection, which hinders the establishment of governmental guidelines in endemic and …

A Trypanosoma cruzi Loopamp kit was recently developed as a ready-to-use diagnostic
method requiring minimal laboratory facilities. We evaluated its diagnostic accuracy for …

Background Trypanosoma cruzi is the causative agent of Chagas disease. Due to its genetic
diversity has been classified into six Discrete Typing Units (DTUs) in association with …

Trypanosoma cruzi, the causal agent of Chagas disease, is mainly transmitted by insects of
the Triatominae subfamily. In Colombia, there are 26 triatomine species, and 16 of them are …