Protein lysine methylation is a crucial post-translational modification that regulates the
functions of both histone and non-histone proteins. Deregulation of the enzymes or 'writers' …

Lung cancer remains one of the most common malignancies in the world. Nowadays, the
most common lung cancer is non-small cell lung cancer (NSCLC), namely …

Regulatory networks that maintain functional, differentiated cell states are often dysregulated
in tumor development. Here, we use single-cell epigenomics to profile chromatin state …

Metastasis, therapy failure and tumour recurrence are major clinical challenges in cancer.
The interplay between tumour‐initiating cells (TICs) and epithelial–mesenchymal transition …

Lung cancer is the most common cancer and the leading cause of cancer-related death
worldwide. However, mechanisms of its progression remained unclear and new treatments …

Mutations in SPOP E3 ligase gene are reportedly associated with genome-wide DNA
hypermethylation in prostate cancer (PCa) although the underlying mechanisms remain …

The histone methyltransferase G9a is well-documented for its implication in neoplastic
growth. However, recent investigations have demonstrated a key involvement of this …

This review delves into the most recent research on the metabolic adaptability of cancer
cells and examines how their metabolic functions can impact their progression into …

The lung microbiome plays an essential role in maintaining healthy lung function, including
host immune homeostasis. Lung microbial dysbiosis or disruption of the gut-lung axis can …

Histone modifications are key factors in chromatin packaging, and are responsible for gene
regulation during cell fate determination and development. Abnormal alterations in histone …