Non-invasive transcranial ultrasound stimulation for neuromodulation

G Darmani, TO Bergmann, KB Pauly, CF Caskey… - Clinical …, 2022 - Elsevier
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …

[HTML][HTML] Human Studies of Transcranial Ultrasound neuromodulation: A systematic review of effectiveness and safety

C Sarica, JF Nankoo, A Fomenko, TC Grippe… - Brain stimulation, 2022 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is gaining traction as a safe and non-
invasive technique in human studies. There has been a rapid increase in TUS human …

Transcranial focused ultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans

SN Yaakub, TA White, J Roberts, E Martin… - Nature …, 2023 - nature.com
Low-intensity transcranial ultrasound stimulation (TUS) is an emerging non-invasive
technique for focally modulating human brain function. The mechanisms and neurochemical …

Ultrasound as a versatile tool for short-and long-term improvement and monitoring of brain function

DG Blackmore, D Razansky, J Götz - Neuron, 2023 - cell.com
Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …

Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology

KR Murphy, JS Farrell, J Bendig, A Mitra, C Luff… - Neuron, 2024 - cell.com
Focused ultrasound can non-invasively modulate neural activity, but whether effective
stimulation parameters generalize across brain regions and cell types remains unknown …

Accelerated transcranial ultrasound neuromodulation in Parkinson's disease: a pilot study

N Samuel, MYR Ding, C Sarica, G Darmani… - Movement …, 2023 - Wiley Online Library
Objective Low‐intensity transcranial focused ultrasound (TUS) is a novel method for
neuromodulation. We aimed to study the feasibility of stimulating the bilateral primary motor …

A causal role of anterior prefrontal-putamen circuit for response inhibition revealed by transcranial ultrasound stimulation in humans

K Nakajima, T Osada, A Ogawa, M Tanaka, S Oka… - Cell Reports, 2022 - cell.com
Stopping an inappropriate response requires the involvement of the prefrontal-subthalamic
hyperdirect pathway. However, how the prefrontal-striatal indirect pathway contributes to …

Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans

BR Kop, YS Oghli, TC Grippe, T Nandi, J Lefkes… - Elife, 2024 - elifesciences.org
Transcranial ultrasonic stimulation (TUS) is rapidly emerging as a promising non-invasive
neuromodulation technique. TUS is already well-established in animal models, providing …

[HTML][HTML] Mechanisms of theta burst transcranial ultrasound induced plasticity in the human motor cortex

YS Oghli, T Grippe, T Arora, T Hoque, G Darmani… - Brain Stimulation, 2023 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is a novel non-invasive brain
stimulation technique with high depth penetrance and spatial resolution. Theta-burst TUS …

[HTML][HTML] Multi-modal investigation of transcranial ultrasound-induced neuroplasticity of the human motor cortex

N Samuel, K Zeng, IE Harmsen, MYR Ding, G Darmani… - Brain Stimulation, 2022 - Elsevier
Introduction There is currently a gap in accessibility to neuromodulation tools that can
approximate the efficacy and spatial resolution of invasive methods. Low intensity …