Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy

A Salihi, MA Al-Naqshabandi… - Molecular …, 2022 - spandidos-publications.com
Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters
that serve a role in regulating normal and pathological cellular activities. They can stimulate …

Chronic inflammation in urothelial bladder cancer

G Nesi, S Nobili, T Cai, S Caini, R Santi - Virchows Archiv, 2015 - Springer
The association between inflammation and cancer has been pointed out in epidemiological
and clinical studies, revealing how chronic inflammation may contribute to carcinogenesis in …

The role of SOD2 and NOS2 genes in the molecular aspect of bladder cancer pathophysiology

R Grębowski, J Saluk, M Bijak, J Szemraj… - Scientific Reports, 2023 - nature.com
Bladder cancer (BC) is a severe health problem of the genitourinary system and is
characterised by a high risk of recurrence. According to the recent GLOBOCAN report …

eNOS genetic polymorphisms and cancer risk: a meta-analysis and a case–control study of breast cancer

X Gao, J Wang, W Wang, M Wang, J Zhang - Medicine, 2015 - journals.lww.com
The association between endothelial nitric oxide synthase (eNOS) polymorphisms (intron
4a/b,-786T> C and 894G> T) and cancer risk remains elusive. In addition, no studies …

Clinically relevant endothelial nitric oxide synthase polymorphisms and their impact on drug response

CK Cotta Filho, GH Oliveira-Paula… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Nitric oxide (NO) is a molecule with multiple functions. Several drugs involve the
modulation of NO levels in their mechanism of action. NO is mainly produced in vessels by …

The T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide synthase gene in prostate cancer cases

SB Diler, A Öden - Russian Journal of Genetics, 2016 - Springer
In previously conducted some studies it has been revealed that nitric oxide (NO) and nitric
oxide synthase (NOS) system play a significant role in carcinogenesis. Nitric oxide (NO) is …

[HTML][HTML] Bladder cancer invasion is mediated by mammalian target of rapamycin complex 2–driven regulation of nitric oxide and invadopodia formation

D Sahu, J Huan, H Wang, D Sahoo, DE Casteel… - The American Journal of …, 2021 - Elsevier
Bladder cancer invasion depends on mammalian target of rapamycin complex 2 (mTORC2)
activity, although the downstream mTORC2 effectors that mediate this effect have not been …

Association between three eNOS polymorphisms and cancer risk: a meta-analysis

X Wu, ZF Wang, Y Xu, R Ren, BL Heng… - Asian Pacific Journal of …, 2014 - koreascience.kr
Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene may influence the risk
of cancer, but the results are still debatable. Therefore, we performed a systematic review to …

[HTML][HTML] Paraoxonase and arylesterase activity in bladder cancer

MM Utanğaç, E Yeni, M Savaş, A Altunkol… - Turkish journal of …, 2017 - ncbi.nlm.nih.gov
Paraoxonase and arylesterase activity in bladder cancer - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide synthase gene in bladder cancer cases

F Polat, SB Diler, I Azazi, A Oden - Asian Pacific Journal of Cancer …, 2015 - koreascience.kr
The aim of the present study was to determine whether endothelial nitric oxide synthase
(eNOS) gene polymorphisms play a role in development of bladder cancer in the Turkish …