Hypertension causes target organ damage (TOD) that involves vasculature, heart, brain and
kidneys. Complex biochemical, hormonal and hemodynamic mechanisms are involved in …

Oxidative stress and mitochondrial dysfunction are associated with the pathogenesis of
several human diseases. The excessive generation of reactive oxygen species (ROS) …

Nitric oxide (NO) can bind to and inhibit the terminal enzyme of the mitochondrial respiratory
chain, cytochrome c oxidase (complex IV). In vivo, NO is made by the NO synthase (NOS) …

Background Nitrosative and oxidative stress play a key role in obesity and diabetes-related
mitochondrial dysfunction. The objective was to investigate the effect of curcumin treatment …

We used laser scanning confocal microscopy in combination with the nitric oxide (NO)‐
sensitive fluorescent dye DAF‐2 and the reactive oxygen species (ROS)‐sensitive dyes CM …

Heart mitochondria play a central role in cell energy provision and in signaling. Nitric oxide
(NO) is a free radical with primary regulatory functions in the heart and involved in a broad …

Nitric oxide (NO) is an important signaling molecule, and a number of NO synthesis
inhibitors and scavengers have been developed to allow study of NO functions and to …

Oxidative stress plays a key role in obesity and diabetes-related mitochondrial dysfunction.
Mitochondrial dysfunction is characterized by increased oxidative damage, nitric oxide (NO) …

The metabolic processes that enable the replication of intracellular Salmonella under
nitrosative stress conditions engendered in the innate response of macrophages are poorly …

Curcumin exhibits several therapeutic properties. Potassium dichromate (K 2 Cr 2 O 7)-
induced nephropathy is associated with oxidative stress. Reactive oxygen species …