Muscle stem cells (MuSCs) are essential for the growth, maintenance, and repair of skeletal
muscle. In the emerging area of cultured meat, meat products are manufactured with MuSCs …

ABSTRACT Myotonic dystrophy type 1 (DM1) is the most prevalent form of muscular
dystrophy in adults and yet there are currently no treatment options. Although this disease …

For cultured meat to succeed at scale, muscle cells from food-relevant species must be
expanded in vitro in a rapid and reliable manner to produce millions of metric tons of …

Antisense oligonucleotides (ASOs) targeting pathologic RNAs have shown promising
therapeutic corrections for many genetic diseases including myotonic dystrophy (DM1) …

Myotonic dystrophy type 1 (DM1) is an incurable neuromuscular disorder caused by an
expanded CTG repeat that is transcribed into r (CUG) exp. The RNA repeat expansion …

Myotonic dystrophy type 1 (DM1) is caused by a highly structured RNA repeat expansion, r
(CUG) exp, harbored in the 3′ untranslated region (3′ UTR) of dystrophia myotonica …

A solid-phase DNA-encoded library (DEL) was studied for binding the RNA repeat
expansion r (CUG) exp, the causative agent of the most common form of adult-onset …

Embryonic myogenesis is a temporally and spatially regulated process that generates
skeletal muscle of the trunk and limbs. During this process, mononucleated myoblasts …

Abstract Myotonic dystrophy type 1 (DM1) is an RNA-dominant disease whose pathogenesis
stems from the functional loss of muscleblind-like RNA-binding proteins (RBPs), which …

Myotonic dystrophy type 1 (DM1) is the most common muscular dystrophy affecting many
different body tissues, predominantly skeletal and cardiac muscles and the central nervous …