Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: artemisinin-peptidyl vinyl phosphonate hybrid molecules as new …
Artemisinin-based combination therapies (ACTs) have been able to reduce the clinical and
pathological malaria cases in endemic areas around the globe. However, recent reports …
pathological malaria cases in endemic areas around the globe. However, recent reports …
Enantioselective synthesis of γ-Phenyl-γ-amino vinyl phosphonates and sulfones and their application to the synthesis of novel highly potent antimalarials
EK Aratikatla, M Kalamuddin, P Malhotra… - ACS …, 2020 - ACS Publications
Racemic and enantioselective syntheses of γ-phenyl-γ-amino vinyl phosphonates and
sulfones have been achieved using Horner–Wadsworth–Emmons olefination of trityl …
sulfones have been achieved using Horner–Wadsworth–Emmons olefination of trityl …