Insulin resistance in depression: A large meta-analysis of metabolic parameters and variation

BS Fernandes, E Salagre, N Enduru, I Grande… - Neuroscience & …, 2022 - Elsevier
Increased insulin resistance is recognized in psychiatric disorders, such as schizophrenia
and bipolar disorder, but its occurrence in depression is less clear. Our aims were to verify if …

Improving functioning, quality of life, and well-being in patients with bipolar disorder

CM Bonnín, M Reinares, A Martínez-Arán… - International Journal …, 2019 - academic.oup.com
People with bipolar disorder frequently experience persistent residual symptoms, problems
in psychosocial functioning, cognitive impairment, and poor quality of life. In the last decade …

Preventive psychiatry: a blueprint for improving the mental health of young people

P Fusar‐Poli, CU Correll, C Arango, M Berk… - World …, 2021 - Wiley Online Library
Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

The use of machine learning techniques in trauma-related disorders: a systematic review

LF Ramos-Lima, V Waikamp… - Journal of psychiatric …, 2020 - Elsevier
Establishing the diagnosis of trauma-related disorders such as Acute Stress Disorder (ASD)
and Posttraumatic Stress Disorder (PTSD) have always been a challenge in clinical practice …

What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group

CRK Ching, DP Hibar, TP Gurholt, A Nunes… - Human brain …, 2022 - Wiley Online Library
MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …

[HTML][HTML] Pharmacogenomics: A road ahead for precision medicine in psychiatry

AF Pardiñas, MJ Owen, JTR Walters - Neuron, 2021 - cell.com
Psychiatric genomics is providing insights into the nature of psychiatric conditions that in
time should identify new drug targets and improve patient care. Less attention has been paid …

Barriers to genetic testing in clinical psychiatry and ways to overcome them: from clinicians' attitudes to sociocultural differences between patients across the globe

J Pinzón-Espinosa, M van der Horst, J Zinkstok… - Translational …, 2022 - nature.com
Genetic testing has evolved rapidly over recent years and new developments have the
potential to provide insights that could improve the ability to diagnose, treat, and prevent …

How to treat mania

I Pacchiarotti, G Anmella, L Colomer… - Acta Psychiatrica …, 2020 - Wiley Online Library
Objective In this paper, we aimed at reviewing evidence‐based treatment options for bipolar
mania and proposed tentative evidence‐based clinical suggestions regarding the …

DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis–A narrative review from the ECNP …

LV Kessing, A González-Pinto, A Fagiolini… - European …, 2021 - Elsevier
This narrative review summarizes and discusses the implications of the Diagnostic and
Statistical Manual of Mental Disorders (DSM)-5 and the upcoming International …

Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores

BJ Coombes, M Markota, JJ Mann, C Colby… - Translational …, 2020 - nature.com
Bipolar disorder (BD) has high clinical heterogeneity, frequent psychiatric comorbidities, and
elevated suicide risk. To determine genetic differences between common clinical sub …