[HTML][HTML] Autonomic nervous system and immune system interactions

MJ Kenney, CK Ganta - Comprehensive physiology, 2014 - ncbi.nlm.nih.gov
The present review assesses the current state of literature defining integrative autonomic-
immune physiological processing, focusing on studies that have employed …

Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis

P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …

Distinct contributions of astrocytes and pericytes to neuroinflammation identified in a 3D human blood-brain barrier on a chip

A Herland, AD van der Meer, EA FitzGerald, TE Park… - PloS one, 2016 - journals.plos.org
Neurovascular inflammation is a major contributor to many neurological disorders, but
modeling these processes in vitro has proven to be difficult. Here, we microengineered a …

Inflammatory disequilibrium in stroke

D Petrovic-Djergovic, SN Goonewardena… - Circulation …, 2016 - Am Heart Assoc
Over the past several decades, there have been substantial advances in our knowledge of
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …

[HTML][HTML] Involvement of pro-and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

JM Ziebell, MC Morganti-Kossmann - Neurotherapeutics, 2010 - Elsevier
Despite dramatic improvements in the management of traumatic brain injury (TBI), to date
there is no effective treatment available to patients, and morbidity and mortality remain high …

Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

Y Katayama, M Battista, WM Kao, A Hidalgo, AJ Peired… - Cell, 2006 - cell.com
Hematopoietic stem and progenitor cells (HSPC), attracted by the chemokine CXCL12,
reside in specific niches in the bone marrow (BM). HSPC migration out of the BM is a critical …

Neurogenesis following stroke affecting the adult brain

O Lindvall, Z Kokaia - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
A bulk of experimental evidence supports the idea that the stroke-damaged adult brain
makes an attempt to repair itself by producing new neurons also in areas where …

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro

E Redondo-Castro, C Cunningham, J Miller… - Stem cell research & …, 2017 - Springer
Background Inflammation is a key contributor to central nervous system (CNS) injury such as
stroke, and is a major target for therapeutic intervention. Effective treatments for CNS injuries …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

The ongoing pursuit of neuroprotective therapies in Parkinson disease

D Athauda, T Foltynie - Nature Reviews Neurology, 2015 - nature.com
Many agents developed for neuroprotective treatment of Parkinson disease (PD) have
shown great promise in the laboratory, but none have translated to positive results in …