miRNA interplay: mechanisms and consequences in cancer

M Hill, N Tran - Disease models & mechanisms, 2021 - journals.biologists.com
Canonically, microRNAs (miRNAs) control mRNA expression. However, studies have shown
that miRNAs are also capable of targeting non-coding RNAs, including long non-coding …

The role of MicroRNAs in human cancer

Y Peng, CM Croce - Signal transduction and targeted therapy, 2016 - nature.com
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

An overview of microRNAs

SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

Clustered miRNAs and their role in biological functions and diseases

SP Kabekkodu, V Shukla, VK Varghese… - Biological …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Noncoding RNA s in disease

E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

Myc and cell cycle control

G Bretones, MD Delgado, J León - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Soon after the discovery of the Myc gene (c-Myc), it became clear that Myc expression levels
tightly correlate to cell proliferation. The entry in cell cycle of quiescent cells upon Myc …

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …

MicroRNAome genome: a treasure for cancer diagnosis and therapy

I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

Induced pluripotent stem cell (iPSC)–derived extracellular vesicles are safer and more effective for cardiac repair than iPSCs

M Adamiak, G Cheng, S Bobis-Wozowicz… - Circulation …, 2018 - Am Heart Assoc
Rationale: Extracellular vesicles (EVs) are tiny membrane-enclosed droplets released by
cells through membrane budding or exocytosis. The myocardial reparative abilities of EVs …

Lung development: orchestrating the generation and regeneration of a complex organ

M Herriges, EE Morrisey - Development, 2014 - journals.biologists.com
The respiratory system, which consists of the lungs, trachea and associated vasculature, is
essential for terrestrial life. In recent years, extensive progress has been made in defining …