A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive …

N Li, S Georas, N Alexis, P Fritz, T Xia… - Journal of Allergy and …, 2016 - Elsevier
Ultrafine particles (UFPs) are airborne particulates of less than 100 nm in aerodynamic
diameter. Examples of UFPs are diesel exhaust particles, products of cooking, heating, and …

Contribution of air pollution to COPD and small airway dysfunction

N Berend - Respirology, 2016 - Wiley Online Library
Although in many Western countries levels of ambient air pollution have been improving
with the setting of upper limits and better urban planning, air pollution in developing …

Outdoor air pollution and new-onset airway disease. An official American Thoracic Society workshop report

GD Thurston, JR Balmes, E Garcia… - Annals of the …, 2020 - atsjournals.org
Although it is well accepted that air pollution exposure exacerbates preexisting airway
disease, it has not been firmly established that long-term pollution exposure increases the …

Effect of NO2 exposure on airway inflammation and oxidative stress in asthmatic mice

C Lu, F Wang, Q Liu, M Deng, X Yang, P Ma - Journal of Hazardous …, 2023 - Elsevier
Nitrogen dioxide (NO 2) is a widespread air pollutant. Epidemiological evidence indicates
that NO 2 is associated with an increase of incidence rate and mortality of asthma, but its …

Association of polycyclic aromatic hydrocarbons exposure with atherosclerotic cardiovascular disease risk: a role of mean platelet volume or club cell secretory protein

C Hu, J Hou, Y Zhou, H Sun, W Yin, Y Zhang… - Environmental …, 2018 - Elsevier
Background Inflammation may play an important role in the association between exposure
to polycyclic aromatic hydrocarbons (PAHs) and atherosclerotic cardiovascular disease …

Mimicking antigen-driven asthma in rodent models—how close can we get?

F Alessandrini, S Musiol, E Schneider… - Frontiers in …, 2020 - frontiersin.org
Asthma is a heterogeneous disease with increasing prevalence worldwide characterized by
chronic airway inflammation, increased mucus secretion and bronchial …

[HTML][HTML] Is pulmonary inflammation a valid predictor of particle induced lung pathology? The case of amorphous and crystalline silicas

CA Poland, R Duffin, K Weber, W Dekant, PJA Borm - Toxicology Letters, 2024 - Elsevier
Although inflammation is a normal and beneficial response, it is also a key event in the
pathology of many chronic diseases, including pulmonary and systemic particle-induced …

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

PN Tsao, SC Wei, MF Wu, MT Huang, HY Lin… - …, 2011 - journals.biologists.com
Goblet cell metaplasia and mucus overproduction contribute to the pathogenesis of chronic
lung diseases, including asthma and chronic obstructive pulmonary disease (COPD). Notch …

Mechanistic insight into the impact of nanomaterials on asthma and allergic airway disease

K Meldrum, C Guo, EL Marczylo, TW Gant… - Particle and Fibre …, 2017 - Springer
Asthma is a chronic respiratory disease known for its high susceptibility to environmental
exposure. Inadvertent inhalation of engineered or incidental nanomaterials is a concern for …

Pro-inflammatory versus immunomodulatory effects of silver nanoparticles in the lung: the critical role of dose, size and surface modification

F Alessandrini, A Vennemann, S Gschwendtner… - Nanomaterials, 2017 - mdpi.com
The growing use of silver nanoparticles (Ag-NPs) in consumer products raises concerns
about their toxicological potential. The purpose of the study was to investigate the size-and …