During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

The gastrointestinal tract maintains energy and glucose homeostasis, in part through
nutrient-sensing and subsequent signaling to the brain and other tissues. In this review, we …

Given the crucial role of the gastrointestinal tract and associated organs in handling nutrient
assimilation and metabolism, it has long been known that its communication with the brain is …

Obesity in women of reproductive age has a number of adverse metabolic effects, including
Type II Diabetes (T2D), dyslipidemia, and cardiovascular disease. It is associated with …

Background Bariatric or weight loss surgery is currently the most effective treatment for
obesity and metabolic disease. Unlike dieting and pharmacology, its beneficial effects are …

Abstract In 1973, Gibbs, Young, and Smith showed that exogenous cholecystokinin (CCK)
administration reduces food intake in rats. This initial report has led to thousands of studies …

Aim The tools that have been used to assess the function of the vagus nerve lack specificity.
This could explain discrepancies about the role of vagal gut‐brain signalling in long‐term …

Cocaine-and amphetamine-related transcript (CART) is a neuropeptide first discovered in
the striatum of the rat brain. Later, the genetic sequence and function of CART peptide …

The jugular-nodose ganglia contain the sensory peripheral neurons of the vagus nerve,
linking visceral organs to the medulla oblongata. Accessing these ganglia in smaller …

The past decades have witnessed the rise and fall of several, largely unsuccessful,
therapeutic attempts to bring the escalating obesity pandemic to a halt. Looking back to look …