[PDF][PDF] Hallmarks of health

C López-Otín, G Kroemer - Cell, 2021 - cell.com
Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

Hydroxytyrosol, tyrosol and derivatives and their potential effects on human health

A Karković Marković, J Torić, M Barbarić… - Molecules, 2019 - mdpi.com
The Mediterranean diet and olive oil as its quintessential part are almost synonymous with a
healthy way of eating and living nowadays. This kind of diet has been highly appreciated …

Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases

C Nediani, J Ruzzolini, A Romani, L Calorini - Antioxidants, 2019 - mdpi.com
Growing scientific literature data suggest that the intake of natural bioactive compounds
plays a critical role in preventing or reducing the occurrence of human chronic non …

Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans

S Rigacci, M Stefani - International journal of molecular sciences, 2016 - mdpi.com
The increasing interest in the Mediterranean diet hinges on its healthy and anti-ageing
properties. The composition of fatty acids, vitamins and polyphenols in olive oil, a key …

Polyphenols as modulator of oxidative stress in cancer disease: new therapeutic strategies

AM Mileo, S Miccadei - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Cancer onset and progression have been linked to oxidative stress by increasing DNA
mutations or inducing DNA damage, genome instability, and cell proliferation and therefore …

Mediterranean diet and the hallmarks of ageing

OM Shannon, AW Ashor, F Scialo, G Saretzki… - European Journal of …, 2021 - nature.com
Ageing is a multifactorial process associated with reduced function and increased risk of
morbidity and mortality. Recently, nine cellular and molecular hallmarks of ageing have …

Cartilage regeneration and ageing: targeting cellular plasticity in osteoarthritis

M Varela-Eirin, J Loureiro, E Fonseca… - Ageing research …, 2018 - Elsevier
Ageing processes play a major contributing role for the development of Osteoarthritis (OA).
This prototypic degenerative condition of ageing is the most common form of arthritis and is …

Inflammaging and cancer: a challenge for the Mediterranean diet

R Ostan, C Lanzarini, E Pini, M Scurti, D Vianello… - nutrients, 2015 - mdpi.com
Aging is considered the major risk factor for cancer, one of the most important mortality
causes in the western world. Inflammaging, a state of chronic, low-level systemic …

Evidence to support the anti-cancer effect of olive leaf extract and future directions

A Boss, KS Bishop, G Marlow, MPG Barnett… - Nutrients, 2016 - mdpi.com
The traditional Mediterranean diet (MD) is associated with long life and lower prevalence of
cardiovascular disease and cancers. The main components of this diet include high intake of …

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

A Sanches-Silva, L Testai, SF Nabavi, M Battino… - Pharmacological …, 2020 - Elsevier
Cardiovascular diseases comprise of non-communicable disorders that involve the heart
and/or blood vessels and have become the leading cause of death worldwide with …