Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Abstract Exosomes are nano-vesicles (30–150 nm) which may be useful as therapeutic
delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the …

To date, the miRNA expression profile of plasma exosomes in women whose pregnancy is
complicated by gestational diabetes mellitus (GDM) has not been fully clarified. In this study …

The mechanisms underlying maternal tolerance of the semi‐or fully‐allogeneic fetus are
intensely investigated. Across gestation, feto‐placental antigens interact with the maternal …

The fetal brain of the mouse is thought to be dependent upon the placenta as a source of
serotonin (5-hydroxytryptamine; 5-HT) and other factors. How factors reach the developing …

Objective To characterize the biochemical and demographic profiles of pregnant people with
maternal immune activation (MIA) and identify the prenatal characteristics associated with …

Preeclampsia (PE) is a common syndrome of pregnancy, characterized by new-onset
hypertension and proteinuria after gestational week 20, or new onset of hypertension and …

胎盘在维持母胎界面的免疫耐受中发挥着关键作用. 近年研究表明, 胎盘合体滋养细胞可以不断
向母体血循环中释放胎盘源性外泌体(placenta-derived exosomes, Pd-Exos), 这些Pd-Exos …

Pregnancy is associated with highly complex changes in a woman's physiology, requiring
multiple developmental, metabolic, endocrine, and immunological pathways to function in a …

Introduction: During pregnancy, the placenta releases significant numbers of extracellular
vesicles (EVs) into the maternal circulation, which are increasingly recognised as essential …