Aquaporins (AQPs) are a family of transmembrane water channel proteins, which were
initially characterized as a novel protein family that plays a vital role in transcellular and …

Aquaporin (AQP) water channels are pivotal to renal water handling and therefore in the
regulation of body water homeostasis. However, beyond the kidney, AQPs facilitate water …

The kidney collecting duct is an important renal tubular segment for regulation of body water
homeostasis and urine concentration. Water reabsorption in the collecting duct principal …

Varieties of Gram-negative bacterial pathogens infect their eukaryotic hosts by deploying the
type III translocon to deliver effector proteins into the cytosol of eukaryotic cells in which …

Cell migration is an essential process that underlies many physiological processes,
including the immune response, organogenesis in the embryo, and angiogenesis, as well as …

Arginine-vasopressin (AVP) stimulates the redistribution of water channels, aquaporin-2
(AQP2) from intracellular vesicles into the plasma membrane of renal collecting duct …

Harpin proteins produced by plant-pathogenic Gram-negative bacteria are the venerable
player in regulating bacterial virulence and inducing plant growth and defenses. A major …

Whole-body water balance is predominantly controlled by the kidneys, which have the ability
to concentrate or dilute the urine in the face of altered fluid and solute intake. Regulated …

In kidney collecting duct cells, filamentous actin (F-actin) depolymerization is a critical step in
vasopressin-induced trafficking of aquaporin-2 to the apical plasma membrane. However …

Abstract The aquaporin 2 (AQP2) water channel, expressed in kidney collecting ducts,
contributes critically to water homeostasis in mammals. Animals lacking or having …