Vascular microphysiological systems

SE Shelton - Current Opinion in Hematology, 2024 - journals.lww.com
These models represent many different types of tissue and disease states. Some devices
have relatively simple geometry and few cell types, while others use complex …

[HTML][HTML] Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling

U Nam, S Lee, A Ahmad, H Yi, JS Jeon - BioChip Journal, 2024 - Springer
The vascular system, essential for human physiology, is vital for transporting nutrients,
oxygen, and waste. Since vascular structures are involved in various disease pathogeneses …

Stable, Conductive, Adhesive Polymer Patterning Inside a Microfluidic Chamber for Endothelial Cell Alignment

E Mancinelli, S Taccola, E Slay… - Advanced Materials …, 2024 - Wiley Online Library
Endothelial cells (ECs) line the inner walls of blood vessels, respond to shear stress by
elongating in the direction of flow. Engineering aligned ECs in vitro is essential for modeling …

[HTML][HTML] Multi-layered Microfluidic Drug Screening Platform Enabling Simultaneous Generation of Linear and Logarithmic Concentration Gradients

JYS Yoon, J Park, H Nam, S Kim, JS Jeon - BioChip Journal, 2024 - Springer
Since many microfluidic devices have limited drug dose order of gradients and incorporate
2D cell culture, we here present a multi-layered platform with linear and logarithmic …

Microfluidic chips as drug screening platforms

I Kim, J Kwon, J Rhyou, JS Jeon - JMST Advances, 2024 - Springer
The selection of a disease model is a crucial factor in drug screening. Research based on
microfluidic chips utilizes various chip designs and cell culture methods to overcome the …