The conditioned place preference (CPP) paradigm is a well-established model utilized to
study the role of context associations in reward-related behaviors, including both natural …

Abstract Matrix metalloproteinase‐9 (MMP‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …

Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly
extracellularly to cleave components of the extracellular matrix, cell adhesion molecules as …

The repeated use of drugs that directly or indirectly stimulate dopamine transmission carry
addiction liability and produce enduring pathological changes in the brain circuitry that …

Matrix metalloproteinases (MMPs) are extracellularly acting enzymes that have long been
known to have deleterious roles in brain injury and disease. In particular, widespread and …

Integrins are a large family of extracellular matrix (ECM) receptors. In the developing and
adult brain, many integrins are present at high levels at synapses. The tetrapartite structure …

Pyramidal neurons in the medial prefrontal cortex (mPFC) critically contribute to cocaine-
seeking behavior in humans and rodents. Activity of these neurons is significantly modulated …

Over the past several years, drug addiction has increasingly been accepted to be a disease
of the brain as opposed to simply being due to a lack of willpower or personality flaw …

Memory consolidation refers to a slow process that stabilises a memory trace after initial
acquisition of novel events. The consolidation theory posits that once a memory is stored in …

Members of the metzincin family of metalloproteinases have long been considered merely
degradative enzymes for extracellular matrix molecules. Recently, however, there has been …