The role of iodine for thyroid function in lactating women and infants

M Andersson, CP Braegger - Endocrine reviews, 2022 - academic.oup.com
Iodine is a micronutrient needed for the production of thyroid hormones, which regulate
metabolism, growth, and development. Iodine deficiency or excess may alter the thyroid …

Stem cells for next level toxicity testing in the 21st century

E Fritsche, T Haarmann‐Stemmann, J Kapr, S Galanjuk… - Small, 2021 - Wiley Online Library
The call for a paradigm change in toxicology from the United States National Research
Council in 2007 initiates awareness for the invention and use of human‐relevant alternative …

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

W Zhou, B Brumpton, O Kabil, J Gudmundsson… - Nature …, 2020 - nature.com
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To
better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis …

The structure of human thyroglobulin

F Coscia, A Taler-Verčič, VT Chang, L Sinn, FJ O'Reilly… - Nature, 2020 - nature.com
Thyroglobulin (TG) is the protein precursor of thyroid hormones, which are essential for
growth, development and the control of metabolism in vertebrates,. Hormone synthesis from …

Selenium, iodine and iron–essential trace elements for thyroid hormone synthesis and metabolism

J Köhrle - International journal of molecular sciences, 2023 - mdpi.com
The adequate availability and metabolism of three essential trace elements, iodine,
selenium and iron, provide the basic requirements for the function and action of the thyroid …

[HTML][HTML] Molecularly imprinted polymer-based sensors for cancer biomarker detection

S Bhakta, P Mishra - Sensors and Actuators Reports, 2021 - Elsevier
Ultrasensitive, quick, and non-invasive recognition of biomarkers is very useful for detection,
screening, and management of cancer effectively. In this regard, there have been enormous …

Pentabromoethylbenzene Exposure Induces Transcriptome Aberration and Thyroid Dysfunction: In Vitro, in Silico, and in Vivo Investigations

L Lu, H Wu, S Cui, T Zhan, C Zhang, S Lu… - Environmental …, 2020 - ACS Publications
Pentabromoethylbenzene (PBEB), as one of the novel brominated flame retardants
(NFBRs), has caused increasing public concern for health risks. Till now, information …

Iodine and thyroid maternal and fetal metabolism during pregnancy

C Mégier, G Dumery, D Luton - Metabolites, 2023 - mdpi.com
Thyroid hormones and iodine are required to increase basal metabolic rate and to regulate
protein synthesis, long bone growth and neuronal maturation. They are also essential for …

[HTML][HTML] Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion

L Jing, Q Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid
gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is …

Nrf2-Mediated antioxidant defense and thyroid hormone signaling: a Focus on Cardioprotective effects

L Sabatino - Antioxidants, 2023 - mdpi.com
Thyroid hormones (TH) perform a plethora of actions in numerous tissues and induce an
overall increase in metabolism, with an augmentation in energy demand and oxygen …