With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …

Aptamers with high affinity and specificity for certain targets have rapidly become a novel
class of targeted ligands applicated in drug delivery. Based on the excellent characteristics …

Abstract Recently, United States Food and Drug Administration (FDA) and European
Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic …

Animal diseases often have significant consequences due to the unclear and time-
consuming diagnosis process. Furthermore, the emergence of new viral infections and drug …

High levels of heat shock protein 70 (HSP70) in tumors are commonly associated with poor
prognosis, enhanced doxorubicin (DOX)-induced cardiotoxicity, and even drug resistance in …

Nanomaterials are at the forefront of health research and development. Among different
nanomaterials, nanoparticles are especially promising for cancer theranostics. However …

The pulmonary delivery of drugs is the most striking target and of incredible scientific and
biomedical attention in the research of health care because the lung is able to absorb …

Highlights•The novel coronavirus crisis caused by SARS-CoV-2 affected the world as a
global pandemic.•Aptamers are single-stranded RNA or DNA oligonucleotides or peptide …

Being the predominant cause of disability, neurological diseases have received much
attention from the global health community. Over a billion people suffer from one of the …

Purpose Effective therapy for rheumatoid arthritis (RA) keeps a challenge due to the
complex pathogenesis of RA. It is not enough to completely inhibit the process of RA with …