[HTML][HTML] HYPE or HOPE: the prognostic value of infiltrating immune cells in cancer

TA Barnes, E Amir - British journal of cancer, 2017 - nature.com
Interactions between immune and malignant cells have been known to have clinical
relevance for decades. The potential for immune control is now being therapeutically …

Bladder cancer, inflammageing and microbiomes

A Martin, BL Woolbright, S Umar, MA Ingersoll… - Nature Reviews …, 2022 - nature.com
Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality.
Advanced age is also associated with elevated markers of chronic inflammation and …

[HTML][HTML] CD68/macrosialin: not just a histochemical marker

DA Chistiakov, MC Killingsworth, VA Myasoedova… - Laboratory …, 2017 - Elsevier
CD68 is a heavily glycosylated glycoprotein that is highly expressed in macrophages and
other mononuclear phagocytes. Traditionally, CD68 is exploited as a valuable cytochemical …

COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells

V Prima, LN Kaliberova, S Kaliberov… - Proceedings of the …, 2017 - National Acad Sciences
In recent years, it has been established that programmed cell death protein ligand 1 (PD-L1)–
mediated inhibition of activated PD-1+ T lymphocytes plays a major role in tumor escape …

The multifaceted immune regulation of bladder cancer

AK Schneider, MF Chevalier, L Derré - Nature Reviews Urology, 2019 - nature.com
Bladder cancer is an important public health concern owing to its prevalence, high
recurrence risk and treatment failures. Maintaining the equilibrium between prompt and …

Functional silver nanoparticle as a benign antimicrobial agent that eradicates antibiotic-resistant bacteria and promotes wound healing

X Dai, Q Guo, Y Zhao, P Zhang, T Zhang… - … applied materials & …, 2016 - ACS Publications
With the increased prevalence of antibiotic-resistant bacteria infections, there is a pressed
need for innovative antimicrobial agent. Here, we report a benign ε-polylysine/silver …

[HTML][HTML] Immune responses in bladder cancer-role of immune cell populations, prognostic factors and therapeutic implications

M Joseph, D Enting - Frontiers in oncology, 2019 - frontiersin.org
Immunosurveillance, which describes the immunologically mediated elimination of
transformed cells, has been widely accepted in the context of bladder cancer for many …

[HTML][HTML] Pparg signaling controls bladder cancer subtype and immune exclusion

T Tate, T Xiang, SE Wobker, M Zhou, X Chen… - Nature …, 2021 - nature.com
Pparg, a nuclear receptor, is downregulated in basal subtype bladder cancers that tend to
be muscle invasive and amplified in luminal subtype bladder cancers that tend to be non …

Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas

SJ Lin, JA Gagnon-Bartsch, IB Tan, S Earle, L Ruff… - Gut, 2015 - gut.bmj.com
Objective Differences in gastric cancer (GC) clinical outcomes between patients in Asian
and non-Asian countries has been historically attributed to variability in clinical …

Immune contexture, immunoscore, and malignant cell molecular subgroups for prognostic and theranostic classifications of cancers

E Becht, NA Giraldo, C Germain, A de Reyniès… - Advances in …, 2016 - Elsevier
The outcome of tumors results from genetic and epigenetic modifications of the transformed
cells and also from the interactions of the malignant cells with their tumor microenvironment …