Cubosomes: the next generation of smart lipid nanoparticles?

HMG Barriga, MN Holme… - Angewandte Chemie …, 2019 - Wiley Online Library
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …

Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine

J Zhai, C Fong, N Tran, CJ Drummond - ACS nano, 2019 - ACS Publications
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …

Lyotropic liquid crystal engineering moving beyond binary compositional space–ordered nanostructured amphiphile self-assembly materials by design

L van't Hag, SL Gras, CE Conn… - Chemical society …, 2017 - pubs.rsc.org
Ordered amphiphile self-assembly materials with a tunable three-dimensional (3D)
nanostructure are of fundamental interest, and crucial for progressing several biological and …

Responsive self-assembled nanostructured lipid systems for drug delivery and diagnostics

WK Fong, R Negrini, JJ Vallooran, R Mezzenga… - Journal of colloid and …, 2016 - Elsevier
While stimuli-responsive polymers have received a huge amount of attention in the
literature, responsive lipid-based mesophase systems offer unique opportunities in …

Electrostatic swelling of bicontinuous cubic lipid phases

AII Tyler, HMG Barriga, ES Parsons, NLC McCarthy… - Soft matter, 2015 - pubs.rsc.org
Lipid bicontinuous cubic phases have attracted enormous interest as bio-compatible
scaffolds for use in a wide range of applications including membrane protein crystallisation …

Coupling lipid nanoparticle structure and automated single‐particle composition analysis to design phospholipase‐responsive nanocarriers

HMG Barriga, IJ Pence, MN Holme… - Advanced …, 2022 - Wiley Online Library
Lipid nanoparticles (LNPs) are versatile structures with tunable physicochemical properties
that are ideally suited as a platform for vaccine delivery and RNA therapeutics. A key barrier …

Lyotropic cubic phases for drug delivery: Diffusion and sustained release from the mesophase evaluated by electrochemical methods

E Nazaruk, P Miszta, S Filipek, E Górecka, EM Landau… - Langmuir, 2015 - ACS Publications
Lyotropic liquid crystalline systems are excellent carriers for drugs due to their
biocompatibility, stability in aqueous environment, and well-defined structure that allow them …

Temperature and pressure tuneable swollen bicontinuous cubic phases approaching nature's length scales

HMG Barriga, AII Tyler, NLC McCarthy, ES Parsons… - Soft Matter, 2015 - pubs.rsc.org
Bicontinuous cubic structures offer enormous potential in applications ranging from protein
crystallisation to drug delivery systems and have been observed in cellular membrane …

Lipidic cubic phases as a versatile platform for the rapid detection of biomarkers, viruses, bacteria, and parasites

JJ Vallooran, S Handschin, SM Pillai… - Advanced functional …, 2016 - Wiley Online Library
Rapid and affordable detection of analytes is critical in diagnostic technologies, but current
methods are typically expensive and unsuitable for field detection. Lipidic cubic phases are …

[HTML][HTML] A novel droplet-based approach to study phase transformations in lyotropic liquid crystalline systems

V He, VJ Cadarso, S Seibt, BJ Boyd, A Neild - Journal of Colloid and …, 2023 - Elsevier
Hypothesis: Lyotropic liquid crystals (LLC) and their phase transformations in response to
stimuli have gathered much interest for controlled and 'on-demand'drug applications. Bulk …