Advances in bioconjugation and native protein modification are appearing at a blistering
pace, making it increasingly time consuming for practitioners to identify the best chemical …

1. INTRODUCTION This review article is concerned with the use of compounds 1 and 2
(Figure 1) as effective and very versatile reagents for trifluoromethylation reactions of a …

1. INTRODUCTION Fluorine is the most abundant halogen in the Earth, s crust. 1 However,
only a dozen fluorinated organic compounds have been identified in nature. 2 Most of the …

Over the past decade, the most significant, conceptual advances in the field of fluorination
were enabled most prominently by organo‐and transition‐metal catalysis. The most …

This review provides a brief assessment of the methodological field of trifluoromethylation
and its possible impact on the development of new CF 3-containing pharmaceuticals …

Die wichtigsten konzeptionellen Fortschritt auf dem Gebiet der Fluorierungen der letzten
zehn Jahre wurden durch die Organo‐und Übergangsmetallkatalyse ermöglicht. Die …

A catalytic protocol to convert aryl and heteroaryl chlorides to the corresponding
trifluoromethyl sulfides is reported herein. It relies on a relatively inexpensive Ni (cod) 2/dppf …

The ever-growing number of fluorinated compounds in medicinal and agrochemical
applications has led to a remarkable positive emulation in research. The last few years have …

In the last decades, hypervalent iodine reagents have raised from chemical curiosities to
mainstream reagents in organic synthesis. The use of benziodoxole-derived reagents has …

While palladium catalysis is ubiquitous in modern chemical research, the recovery of the
active transition‐metal complex under routine laboratory applications is frequently …