Cardiac electrophysiology models are among the most mature and well‐studied
mathematical models of biological systems. This maturity is bringing new challenges as …

Accurately inferring underlying electrophysiological (EP) tissue properties from action
potential recordings is expected to be clinically useful in the diagnosis and treatment of …

This work introduces a comprehensive approach to assess the sensitivity of model outputs to
changes in parameter values, constrained by the combination of prior beliefs and data. This …

Quantitative modelling is increasingly important in cancer research, helping to integrate
myriad diverse experimental data into coherent pictures of the disease and able to …

The understanding of complex physical or biological systems nearly always requires a
characterization of the variability that underpins these processes. In addition, the data used …

Mechanisms of atrial fibrillation and the susceptibility to reentries can be impacted by the
repolarization across the atria. Studies into atrial fibrillation ignore cell-to-cell heterogeneity …

Variability refers to differences in physiological function between individuals, which may
translate into different disease susceptibility and treatment efficacy. Experiments in human …

Computational modelling, combined with experimental investigations, is a powerful method
for investigating complex cardiac electrophysiological behaviour. The use of rabbit-specific …

The variability observed in action potential (AP) cardiomyocyte measurements is the
consequence of many different sources of randomness. Often ignored, this variability may be …

ABSTRACT The Beeler–Reuter model is one of the oldest models of the cardiac ventricular
cell. This model is used in many scientific studies that investigate the propagation of the …