[HTML][HTML] eQTL studies: from bulk tissues to single cells
An expression quantitative trait locus (eQTL) is a chromosomal region where genetic
variants are associated with the expression levels of specific genes that can be both nearby …
variants are associated with the expression levels of specific genes that can be both nearby …
[HTML][HTML] Mapping the landscape of lineage-specific dynamic regulation of gene expression using single-cell transcriptomics and application to genetics of complex …
Single-cell transcriptome data can provide insights into how genetic variation influences
biological processes involved in human biology and disease. However, the identification of …
biological processes involved in human biology and disease. However, the identification of …
Statistical Models for Single-Cell Genetics
T Heinen - 2024 - archiv.ub.uni-heidelberg.de
The impact of genetic variation on molecular traits such as gene expression is known to vary
substantially across molecular contexts, such as cell types and states. Conventional …
substantially across molecular contexts, such as cell types and states. Conventional …