[HTML][HTML] Deubiquitinases in muscle physiology and disorders
CS Olie, DP O'Brien, HBL Jones, Z Liang… - Biochemical Society …, 2024 - portlandpress.com
In vivo, muscle and neuronal cells are post-mitotic, and their function is predominantly
regulated by proteostasis, a multilayer molecular process that maintains a delicate balance …
regulated by proteostasis, a multilayer molecular process that maintains a delicate balance …
去泛素化酶OTUB1 参与细胞铜缺乏的应答
张宇飞， 朱基彦， 瞿思遥， 张祝琴… - 基础医学与 …, 2022 - journal11.magtechjournal.com
目的通过构建铜缺乏的细胞模型探究是否存在铜依赖的酶参与铜缺乏导致的心肌肥厚的发生.
方法使用CRISPR/Cas9 技术, 构建Ctr1 基因敲除的大鼠心肌细胞株H9c2 (Ctr1-/-); …
方法使用CRISPR/Cas9 技术, 构建Ctr1 基因敲除的大鼠心肌细胞株H9c2 (Ctr1-/-); …
Deubiquitinase OTUB1 is involved in the cellular response to copper deficiency
Y ZHANG, J ZHU, S QU… - Basic & Clinical …, 2022 - journal11.magtechjournal.com
Objective By establishing a copper deficiency cell model to explore whether there are
copper-dependent enzymes involved in cardiac hypertrophy caused by copper deficiency …
copper-dependent enzymes involved in cardiac hypertrophy caused by copper deficiency …