Sustained-release formulations of analgesic drugs are promising alternatives to repeated
drug injections. Here, we compared a sustained-release formulation of buprenorphine (SB …

C57BL/6NCrl male mice (n= 60; age, 6 to 7 wk) underwent partial hepatectomy or no
surgery and were given 1 of 3 analgesics pre-and postoperatively. Food and water …

Traumatic spinal cord injury (SCI) promotes long-term disability that affects mobility and
functional independence. The spinal cord inflammatory response after the initial mechanical …

An adequate analgesic strategy is important to improve the postoperative recovery and
welfare of laboratory rats and mice. It is desirable that the method for administering the drug …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Oral administration of substances is a common procedure in scientific experiments using
laboratory animals and typically is achieved in conscious animals by using the intragastric …

Stress can influence a number of physiological processes including adult neurogenesis,
metabolism, cardiovascular function, immune function, neurophysiological function …

Facial vein (cheek blood) and caudal vein (tail blood) phlebotomy are two commonly used
techniques for obtaining blood samples from laboratory mice, while automated blood …

This study investigated the effects of surgical placement of permanent arterial catheters on
plasma corticosterone levels, fecal corticosterone excretion and body weight in male …

Complete Freund's adjuvant (CFA)-induced arthritis in rats is a common animal model for
studying chronic inflammatory pain. However, modelling of the disease is associated with …