The vascular blood–brain barrier is a highly regulated interface between the blood and
brain. Its primary function is to protect central neurons while signaling the presence of …

The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons
and inflammatory responses. Whereas microglia are very competent phagocytes under …

The blood–brain barrier (BBB) is the neurovascular structure that regulates the passage of
cells and molecules to and from the central nervous system (CNS). Alzheimer's disease (AD) …

Stroke is accounted as the second-most mortality and adult disability factor in worldwide,
while causes the bleeding promptly and lifetime consequences. The employed functional …

Antibody–drug conjugates (ADCs) have recently demonstrated impressive successes in
targeted drug delivery. Ultrasmall (< 10 nm) nanoparticle–drug conjugates (NDCs) share …

The development of clinical imaging techniques significantly improves diagnostic accuracy
and provides guidance for personalized treatment of individuals. However, every single …

Traumatic brain injury (TBI) is a leading cause of death and disability, especially in young
persons, and constitutes a major socioeconomic burden worldwide. It is regarded as the …

Disruption of the blood–brain barrier (BBB) is an important pathological hallmark of ischemic
stroke. Blood–brain barrier disruption (BBBD) is a consequence of ischemia and may also …

Stroke is a major public health issue, corresponding to the second cause of mortality and the
first cause of severe disability. Ischemic stroke is the most common type of stroke …