[HTML][HTML] Leukotrienes vs. montelukast—activity, metabolism, and toxicity hints for repurposing
Increasing environmental distress is associated with a growing asthma incidence; no
treatments are available but montelukast (MTK)—an antagonist of the cysteinyl leukotrienes …
treatments are available but montelukast (MTK)—an antagonist of the cysteinyl leukotrienes …
[HTML][HTML] Interaction of medicinal plants and their active constituents with potassium ion channels: A systematic review
A Rajabian, F Rajabian, F Babaei… - Frontiers in …, 2022 - frontiersin.org
Potassium ion (K+) channels are pore-forming transmembrane proteins that control the
transport of K+ ions. Medicinal plants are widely used as complementary therapies for …
transport of K+ ions. Medicinal plants are widely used as complementary therapies for …
[HTML][HTML] Leukotriene receptor antagonist, montelukast ameliorates L-Name-induced pre-eclampsia in rats through suppressing the IL-6/Jak2/STAT3 signaling pathway
WY Abdelzaher, G Mostafa-Hedeab, HA Bahaa… - Pharmaceuticals, 2022 - mdpi.com
Aims: To investigate the potential protective role of montelukast (Mont) in the pre-eclampsia
rat model induced by L-NG-Nitro arginine methyl ester (L-NAME). Methods and materials …
rat model induced by L-NG-Nitro arginine methyl ester (L-NAME). Methods and materials …
[HTML][HTML] The effect of montelukast, a leukotriene receptor antagonist, on the acetic acid-induced model of colitis in rats: Involvement of NO-cGMP-KATP channels …
B Ghorbanzadeh, MA Behmanesh… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease is a chronic autoimmune disorder that may involve entire
gastrointestinal tract. The leukotrienes have a role as mediators in the pathophysiology of …
gastrointestinal tract. The leukotrienes have a role as mediators in the pathophysiology of …
The nitric oxide-cyclic GMP-KATP channels pathway contributes to the effects of montelukast against gastric damage induced by ethanol
MA Behmanesh, A Rasekhian, F Kiani… - Alcohol, 2023 - Elsevier
The leukotrienes, lipid mediators, have a role in gastric damage induced by ethanol. Here,
the gastroprotective effect of montelukast, an antagonist of the leukotriene receptor, and the …
the gastroprotective effect of montelukast, an antagonist of the leukotriene receptor, and the …
[PDF][PDF] Anti-enzymatic and DNA docking studies of montelukast: A multifaceted molecular scaffold with in vitro investigations, molecular expression analysis and …
Montelukast, an approved leukotriene receptor 1 (Cys-LT 1) antagonist with anti-
inflammatory properties is used for the treatment of asthma and allergic rhinitis. In the …
inflammatory properties is used for the treatment of asthma and allergic rhinitis. In the …
Effect of nitric oxide–cyclic GMP–K+ channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom
MI Ortiz, R Cariño-Cortés… - Canadian Journal of …, 2022 - cdnsciencepub.com
Pamabrom is a diuretic that is effective in treating premenstrual syndrome and primary
dysmenorrhea. The aim of this study was to examine the effect of metformin and modulators …
dysmenorrhea. The aim of this study was to examine the effect of metformin and modulators …
Role of the NO-cGMP-K+ channels pathway in the peripheral antinociception induced by α-bisabolol
MI Ortiz, R Cariño-Cortés… - Canadian Journal of …, 2021 - cdnsciencepub.com
The aim of this study was to examine if the peripheral antinociception of α-bisabolol involves
the participation of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) synthesis …
the participation of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) synthesis …
The role of l-arginine/NO/cGMP/KATP channel pathway in the local antinociceptive effect of berberine in the rat formalin test
M Rahemi, S Mohtadi, HR Vardanjani… - Behavioural …, 2023 - journals.lww.com
Berberine is an isoquinoline alkaloid naturally produced by several types of plants.
Berberine has extensive pharmacological effects, such as anti-diabetic, anti-inflammatory …
Berberine has extensive pharmacological effects, such as anti-diabetic, anti-inflammatory …
Analgesic and Anti-inflammatory Effects of Montelukast in Chicks
The goal of the study was to assess the analgesic and anti-inflammatory properties of
montelukast in chicks. Methods: The oral median analgesic effective dose (ED50) of …
montelukast in chicks. Methods: The oral median analgesic effective dose (ED50) of …