Acinetobacter metabolism in infection and antimicrobial resistance

X Ren, LD Palmer - Infection and Immunity, 2023 - Am Soc Microbiol
Acinetobacter infections have high rates of mortality due to an increasing incidence of
infections by multidrug-resistant (MDR) and extensively-drug-resistant (XDR) strains …

Model architectures for bacterial membranes

AB Carey, A Ashenden, I Köper - Biophysical reviews, 2022 - Springer
The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …

Shigella flexneri Adapts to Niche-Specific Stresses through Modifications in Cell Envelope Composition and Decoration

A Ascari, JK Waters, R Morona… - ACS Infectious …, 2023 - ACS Publications
Shigella flexneri is the primary causative agent of worldwide shigellosis. As the pathogen
transverses the distinct niches of the gastrointestinal tract it necessitates dynamic adaptation …

Characterization of pyridylpiperazine-based efflux pump inhibitors for Acinetobacter baumannii

JC Jiménez-Castellanos, E Pradel… - JAC-Antimicrobial …, 2023 - academic.oup.com
Abstract Objectives In Acinetobacter baumannii, multidrug efflux pumps belonging to the
resistance-nodulation-division (RND) superfamily result in decreased antibiotic …

[HTML][HTML] Characterizing the role of phosphatidylglycerol-phosphate phosphatases in Acinetobacter baumannii cell envelope biogenesis and antibiotic resistance

M Zang, A Ascari, FG Adams, S Alquethamy… - The Cell Surface, 2023 - Elsevier
The dissemination of multi-drug resistant Acinetobacter baumannii threatens global
healthcare systems and necessitates the development of novel therapeutic options. The …

The impact of omega-3 fatty acids on the evolution of Acinetobacter baumannii drug resistance

M Zang, FG Adams, KA Hassan… - Microbiology …, 2021 - Am Soc Microbiol
The bacterial pathogen Acinetobacter baumannii has emerged as an urgent threat to health
care systems. The prevalence of multidrug resistance in this critical human pathogen is …

[HTML][HTML] Advancing engineered approaches for sustainable wound regeneration and repair: Harnessing the potential of green synthesized silver nanoparticles

J Nandhini, E Karthikeyan, EE Rani, VS Karthikha… - Engineered …, 2024 - Elsevier
Wound healing is a crucial biological process for tissue repair and regeneration, preventing
infections and complications. There's been a growing interest in exploring sustainable …

Salinity and hydraulic retention time induce membrane phospholipid acyl chain remodeling in Halanaerobium congolense WG10 and mixed cultures from …

CJ Ugwuodo, F Colosimo, J Adhikari, Y Shen… - Frontiers in …, 2022 - frontiersin.org
Bacteria remodel their plasma membrane lipidome to maintain key biophysical attributes in
response to ecological disturbances. For Halanaerobium and other anaerobic halotolerant …

Lipidome of Acinetobacter baumannii antibiotic persister cells

D Vergoz, A Schaumann, I Schmitz, C Afonso… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Persister cells constitute a bacterial subpopulation able to survive to high concentrations of
antibiotics. This phenotype is temporary and reversible, and thus could be involved in the …

Acinetobacter baumannii Fatty Acid Desaturases Facilitate Survival in Distinct Environments

FG Adams, A Pokhrel, EB Brazel… - ACS Infectious …, 2021 - ACS Publications
Maintaining optimal fluidity is essential to ensure adequate membrane structure and function
under different environmental conditions. We apply integrated molecular approaches to …