Vitamin C and cardiovascular disease: an update
MB Morelli, J Gambardella, V Castellanos, V Trimarco… - Antioxidants, 2020 - mdpi.com
The potential beneficial effects of the antioxidant properties of vitamin C have been
investigated in a number of pathological conditions. In this review, we assess both clinical …
investigated in a number of pathological conditions. In this review, we assess both clinical …
Nitric oxide in cellular adaptation and disease
BN Gantner, KM LaFond, MG Bonini - Redox Biology, 2020 - Elsevier
Nitric oxide synthases are the major sources of nitric oxide, a critical signaling molecule
involved in a wide range of cellular and physiological processes. These enzymes comprise …
involved in a wide range of cellular and physiological processes. These enzymes comprise …
Systemic perturbations in amine and kynurenine metabolism associated with acute SARS-CoV-2 infection and inflammatory cytokine responses
We performed quantitative metabolic phenotyping of blood plasma in parallel with
cytokine/chemokine analysis from participants who were either SARS-CoV-2 (+)(n= 10) or …
cytokine/chemokine analysis from participants who were either SARS-CoV-2 (+)(n= 10) or …
Kynurenic acid may underlie sex-specific immune responses to COVID-19
Coronavirus disease 2019 (COVID-19) has poorer clinical outcomes in males than in
females, and immune responses underlie these sex-related differences. Because immune …
females, and immune responses underlie these sex-related differences. Because immune …
A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach
J Singh, Y Lee, JA Kellum - Critical Care, 2022 - Springer
The nitric oxide pathway plays a critical role in vascular homeostasis. Increased levels of
systemic nitric oxide (NO) are observed in preclinical models of sepsis and endotoxemia …
systemic nitric oxide (NO) are observed in preclinical models of sepsis and endotoxemia …
Combined metabolic activators accelerates recovery in mild‐to‐moderate COVID‐19
COVID‐19 is associated with mitochondrial dysfunction and metabolic abnormalities,
including the deficiencies in nicotinamide adenine dinucleotide (NAD+) and glutathione …
including the deficiencies in nicotinamide adenine dinucleotide (NAD+) and glutathione …
Preventing bacterial translocation in patients with leaky gut syndrome: Nutrition and pharmacological treatment options
A Twardowska, A Makaro, A Binienda, J Fichna… - International journal of …, 2022 - mdpi.com
Leaky gut syndrome is a medical condition characterized by intestinal hyperpermeability.
Since the intestinal barrier is one of the essential components maintaining homeostasis …
Since the intestinal barrier is one of the essential components maintaining homeostasis …
Citrulline in health and disease. Review on human studies
C Papadia, S Osowska, L Cynober, A Forbes - Clinical Nutrition, 2018 - Elsevier
The amino acid L-citrulline (CIT) is safely used from the neonatal period onwards in those
with urea cycle defects and carbamyl phosphate synthetase or ornithine transcarbamylase …
with urea cycle defects and carbamyl phosphate synthetase or ornithine transcarbamylase …
Boosting NAD preferentially blunts Th17 inflammation via arginine biosynthesis and redox control in healthy and psoriasis subjects
To evaluate whether nicotinamide adenine dinucleotide-positive (NAD+) boosting
modulates adaptive immunity, primary CD4+ T cells from healthy control and psoriasis …
modulates adaptive immunity, primary CD4+ T cells from healthy control and psoriasis …
Could metabolomics drive the fate of COVID-19 pandemic? A narrative review on lights and shadows
Abstract Human Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2)
infection activates a complex interaction host/virus, leading to the reprogramming of the host …
infection activates a complex interaction host/virus, leading to the reprogramming of the host …