Approximately 100,000 primary and metastatic brain tumor patients/year in the US survive
long enough (> 6 months) to experience radiation-induced brain injury. Prior to 1970, the …

Although low-grade gliomas (LGG) have a less aggressive course than do high-grade
gliomas, the outcome of these tumours is ultimately fatal in most patients. Both the tumour …

Background Our previous study on cognitive functioning among 195 patients with low-grade
glioma (LGG) a mean of 6 years after diagnosis suggested that the tumour itself, rather than …

Cognitive function, with survival and response on brain imaging, is increasingly regarded as
an important outcome measure in patients with brain tumours. This measure provides us …

Background Postoperative policies of" wait-and-see" and radiotherapy for low-grade glioma
are poorly defined. A trial in the mid 1980s established the radiation dose. In 1986 the …

Background: Diffuse infiltrative low‐grade gliomas of the cerebral hemispheres in the adult
are a group of tumors with distinct clinical, histological and molecular characteristics, and …

Background Because survival benefits of treatment with radiotherapy are questionable and
such treatment can cause substantial damage to the brain over time, the optimum …

Neuropsychiatric problems, and how they interact to impact on quality of life (QOL) in brain
tumor patients, are generally poorly understood. The objectives of this study were:(1) to …

PURPOSE Patients with malignant glioma develop progressive neurobehavioral deficits
over the course of their illness. These are caused both by the effects of the disease and the …

Quality of life is an important area of clinical neurooncology that is increasingly relevant as
survivorship increases and as patients experience potential morbidities associated with new …