Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview

N Lampiasi, R Bonaventura, I Deidda, F Zito… - International Journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous collection of neurodevelopmental
disorders, difficult to diagnose and currently lacking treatment options. The possibility of …

Semaphorin 3 A influences neuronal processes that are altered in patients with autism spectrum disorder: potential diagnostic and therapeutic implications

C Matrone, G Ferretti - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Autism spectrum disorder (ASD) is a pervasive disorder that most frequently manifests in
early childhood and lasts for their entire lifespan. Several behavioural traits characterise the …

A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders

L Lombardi, S Le Clerc, CL Wu, J Bouassida… - Translational …, 2023 - nature.com
Autism spectrum disorders (ASD) are neurodevelopmental conditions that are for subsets of
individuals, underpinned by dysregulated immune processes, including inflammation …

Gene× environment interactions in autism spectrum disorders

K Keil-Stietz, PJ Lein - Current topics in developmental biology, 2023 - Elsevier
There is credible evidence that environmental factors influence individual risk and/or
severity of autism spectrum disorders (hereafter referred to as autism). While it is likely that …

Conceptualizing Epigenetics and the Environmental Landscape of Autism Spectrum Disorders

G Torres, M Mourad, S Iqbal, E Moses-Fynn, A Pandita… - Genes, 2023 - mdpi.com
Complex interactions between gene variants and environmental risk factors underlie the
pathophysiological pathways in major psychiatric disorders. Autism Spectrum Disorder is a …

Steroid hormone pathways, vitamin D and autism: a systematic review

A Amestoy, C Baudrillard, K Briot, A Pizano… - Journal of Neural …, 2023 - Springer
The origins of the male preponderance in autism incidence remain unclear. The idea that
perinatal factors associated with sex differentiation (eg, steroid hormone pathways) may …

Metabolic network analysis of pre-ASD newborns and 5-year-old children with autism spectrum disorder

SS Lingampelly, JC Naviaux, LS Heuer… - Communications …, 2024 - nature.com
Classical metabolomic and new metabolic network methods were used to study the
developmental features of autism spectrum disorder (ASD) in newborns (n= 205) and 5-year …

Plasma cytokine concentrations of children with autism spectrum disorder and neurotypical siblings

I Belica, K Janšáková, H Celušáková, M Kopčíková… - Cytokine, 2023 - Elsevier
Several studies of autism spectrum disorder (ASD) have shown cytokine dysregulation in
children with ASD, leading to a consideration of the immune theory of the ASD …

Unveiling the interplay between NSAID-induced dysbiosis and autoimmune liver disease in children: insights into the hidden gateway to autism spectrum disorders …

DI Mohamed, HH Abo Nahas, AM Elshaer… - Frontiers in Cellular …, 2023 - frontiersin.org
Autism spectrum disorders (ASD) represent a diverse group of neuropsychiatric conditions,
and recent evidence has suggested a connection between ASD and microbial dysbiosis …

Differential expression of endogenous retroviruses and inflammatory mediators in female and male offspring in a mouse model of maternal immune activation

C Cipriani, AM Tartaglione, M Giudice… - International Journal of …, 2022 - mdpi.com
Maternal infections during pregnancy and the consequent maternal immune activation (MIA)
are the major risk factors for autism spectrum disorder (ASD). Epidemiological evidence is …