[HTML][HTML] Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

[HTML][HTML] Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma

A WellsSamuel Jr, L AsaSylvia, B EvansDouglas… - Thyroid, 2015 - liebertpub.com
Abstract Introduction: The American Thyroid Association appointed a Task Force of experts
to revise the original Medullary Thyroid Carcinoma: Management Guidelines of the …

Cabozantinib in progressive medullary thyroid cancer

R Elisei, MJ Schlumberger, SP Müller… - Journal of clinical …, 2013 - ascopubs.org
Purpose Cabozantinib, a tyrosine kinase inhibitor (TKI) of hepatocyte growth factor receptor
(MET), vascular endothelial growth factor receptor 2, and rearranged during transfection …

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

Anlotinib in locally advanced or metastatic medullary thyroid carcinoma: a randomized, double-blind phase IIB trial

D Li, Y Chi, X Chen, M Ge, Y Zhang, Z Guo… - Clinical Cancer …, 2021 - AACR
Purpose: Medullary thyroid cancer (MTC) accounts for about 2% of all thyroid cancer, but
has a relatively poor prognosis compared with differentiated thyroid cancer. Anlotinib is a …

A phase II trial of the multitargeted tyrosine kinase inhibitor lenvatinib (E7080) in advanced medullary thyroid cancer

M Schlumberger, B Jarzab, ME Cabanillas… - Clinical Cancer …, 2016 - AACR
Purpose: Positive results of phase I studies evaluating lenvatinib in solid tumors, including
thyroid cancer, prompted a phase II trial in advanced medullary thyroid carcinoma (MTC) …

[HTML][HTML] Medullary thyroid carcinoma beyond surgery: advances, challenges, and perspectives

L Ceolin, MA da Silveira Duval… - Endocrine-related …, 2019 - erc.bioscientifica.com
Medullary thyroid carcinoma (MTC) is a rare type of tumor that originates from thyroid C cells
and accounts for 2–4% of all malignant thyroid neoplasms. MTC may occur sporadically or …

[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: Progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - Biochimica et Biophysica …, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. Surgery,
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …

Anlotinib for the treatment of patients with locally advanced or metastatic medullary thyroid cancer

Y Sun, F Du, M Gao, Q Ji, Z Li, Y Zhang, Z Guo, J Wang… - Thyroid, 2018 - liebertpub.com
Background: The prognosis of advanced or metastatic medullary thyroid carcinoma (MTC) is
poor, and there are few therapeutic options. Anlotinib has previously shown promising …

[HTML][HTML] Treatment of advanced thyroid cancer with targeted therapies: ten years of experience

D Viola, L Valerio, E Molinaro, L Agate… - Endocrine-related …, 2016 - erc.bioscientifica.com
Thyroid cancer is rare, but it is the most frequent endocrine malignancy. Its prognosis is
generally favorable, especially in cases of well-differentiated thyroid cancers (DTCs), such …