Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders

FX Vollenweider, KH Preller - Nature Reviews Neuroscience, 2020 - nature.com
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review

M van Elk, DB Yaden - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

[HTML][HTML] REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics

RL Carhart-Harris, KJ Friston - Pharmacological reviews, 2019 - ASPET
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Psychedelics and psychedelic-assisted psychotherapy

CM Reiff, EE Richman, CB Nemeroff… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

Models of psychedelic drug action: modulation of cortical-subcortical circuits

MK Doss, MB Madden, A Gaddis, MB Nebel… - Brain, 2022 - academic.oup.com
Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine

D De Gregorio, A Aguilar-Valles, KH Preller… - Journal of …, 2021 - Soc Neuroscience
A revamped interest in the study of hallucinogens has recently emerged, especially with
regard to their potential application in the treatment of psychiatric disorders. In the last …

Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi - Pharmacological Reviews, 2021 - ASPET
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Psychedelics

DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

A neurophenomenological approach to non-ordinary states of consciousness: hypnosis, meditation, and psychedelics

C Timmermann, PR Bauer, O Gosseries… - Trends in cognitive …, 2023 - cell.com
No contemporary unifying framework has been provided for the study of non-ordinary states
of consciousness (NSCs) despite increased interest in hypnosis, meditation, and …