RNA ac4C modification is a novel and rare chemical modification observed in mRNA.
Traditional biochemical studies had primarily associated ac4C modification with tRNA and …

Messenger RNA (mRNA) vaccines are third‐generation nucleic acid vaccines developed
after first‐generation inactivated and live‐attenuated vaccines and second‐generation …

RNA structure determination and prediction can promote RNA-targeted drug development
and engineerable synthetic elements design. But due to the intrinsic structural flexibility of …

Ribonucleic acids (RNAs) remain challenging targets for structural biology, creating barriers
to understanding their vast functions in cellular biology and fully realizing their applications …

We describe the modeling method for RNA tertiary structures employed by team
AIchemy_RNA2 in the 15th Critical Assessment of Structure Prediction (CASP15). The …

Ferroptosis, a unique type of non-apoptotic cell death resulting from iron-dependent lipid
peroxidation, has a potential physiological function in tumor suppression, but its underlying …

Riboswitches are conserved non-coding domains in bacterial mRNA with gene regulation
function that are essential for maintaining enzyme co-factor metabolism. Recently, the pnuC …

The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …

Riboswitches are highly conserved RNA elements that located in the 5′-UTR of mRNAs,
which undergo real-time structure conformational change to achieve the regulation of …

Over recent years, long-range RNA structure has emerged as a factor that is fundamental to
alternative splicing regulation. An increasing number of human disorders are now being …