In this review we summarize recent major advances in our understanding on the molecular
mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary …

The capacity of organisms to sense changes in the levels of internal and external gases and
to respond accordingly is central to a range of physiologic and pathophysiologic processes …

Purpose To analyze the relationship between hypercapnia developing within the first 48 h
after the start of mechanical ventilation and outcome in patients with acute respiratory …

Hypercapnia, an elevation of the level of carbon dioxide (CO2) in blood and tissues, is a
marker of poor prognosis in chronic obstructive pulmonary disease and other pulmonary …

Inflammation, although necessary to fight infections, becomes a threat when it exceeds the
capability of the immune system to control it. In addition, inflammation is a cause and/or …

Triphenyl phosphate (TPHP) is a widely used aryl organophosphate flame retardant (OPFR)
that has attracted attention due to its frequent detection in the environment and living …

A significant number of patients with coronavirus disease 2019 (COVID-19) develop acute
respiratory distress syndrome (ARDS) that is associated with a poor outcome. The molecular …

Gases are sensed by lung cells and can activate specific intracellular signalling pathways,
and thus have physiological and pathophysiological effects. Carbon dioxide (CO2), a …

Permissive hypercapnia: what to remember : Current Opinion in Anesthesiology Permissive
hypercapnia: what to remember : Current Opinion in Anesthesiology Log in or Register …

Molecular oxygen and carbon dioxide are the primary gaseous substrate and product of
oxidative metabolism, respectively. Hypoxia (low oxygen) and hypercapnia (high carbon …